Matrix information:
(Help) ADAN-name: 1HCS2.PDB Scoring matrix: 1HCS2_mat Uniprot code: P12931 Genome source: Homo sapiens Wild-type ligand: yEEIE Foldx wt ligand score: 3.64 Foldx random average score for Homo sapiens: 6.811 Available information for P12931 in MINT (Nov 2008): Nš of interacting proteins: 50 Proteins belonging to other specie: 11 Nš of interactions described: 106 Interactions with other species: 20
Genome scanning information:
Subcellular location: False Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0 Proteins considered as fragments or having non-standard amino acids: 22829 Total scanned proteins: 48061 Total fragments: 22344792 Proteins after random average filtering: 48054 Total fragments: 12510712 Proteins after disorder filtering: 37622 Total fragments: 1544739 Proteins after pattern filtering: 16247 Total fragments: 50736 Proteins after MINT filtering: 22 Total fragments: 102
Prediction of know targets:
Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
Reference wt |
yEEIE |
3.64
|
-5.28 |
0.00 |
Best peptides |
DECIy |
0.00
|
-0.78 |
4.50 |
|
|
|
|
|
Interactors |
|
|
|
|
P49023 |
YQEIA |
4.33
|
-3.37 |
1.91 |
|
YGVPE |
5.76
|
-1.39 |
3.89 |
|
PLYGV |
5.89
|
-1.90 |
3.38 |
Q8WUM4 |
YNMPY |
5.22
|
-1.18 |
4.10 |
|
PSYPF |
5.53
|
-2.18 |
3.10 |
|
YPPVY |
5.55
|
-1.67 |
3.61 |
Q16832 |
YDRIF |
3.54
|
-2.92 |
2.36 |
|
PYDIF |
3.65
|
-2.75 |
2.53 |
|
YDPML |
4.01
|
-3.36 |
1.92 |
P15941 |
YEKVS |
3.79
|
-2.99 |
2.29 |
|
SEYPT |
4.79
|
-2.61 |
2.67 |
|
YVPPS |
5.68
|
-2.82 |
2.46 |
P09848 |
YDTIG |
3.11
|
-3.51 |
1.77 |
|
YGTAA |
6.68
|
-0.18 |
5.10 |
P05106 |
YMYIS |
3.70
|
-4.26 |
1.02 |
|
SPYMY |
5.68
|
-0.12 |
5.16 |
|
YCNCT |
6.09
|
-1.37 |
3.91 |
P00533 |
YQDPH |
5.16
|
-1.34 |
3.94 |
|
LYNPT |
5.81
|
-2.22 |
3.06 |
|
PDYQQ |
6.75
|
-1.23 |
4.05 |
P22681 |
YMTPS |
3.85
|
-3.88 |
1.40 |
|
YDVPK |
4.49
|
-2.79 |
2.49 |
|
TEYMT |
4.59
|
-1.77 |
3.51 |
Q05655 |
YGKIW |
4.73
|
-1.64 |
3.64 |
P03372 |
PYGPG |
5.15
|
-2.39 |
2.89 |
|
GYTVR |
6.38
|
-1.09 |
4.19 |
Q8TBB1 |
PAYVS |
5.62
|
-2.58 |
2.70 |
P25092 |
TYPVD |
6.41
|
-1.12 |
4.16 |
Q05397 |
YQPVG |
4.76
|
-2.65 |
2.63 |
|
YPSPQ |
5.72
|
-1.36 |
3.92 |
|
YPSPR |
6.05
|
-1.23 |
4.05 |
Q9C0H9 |
PLYGD |
5.49
|
-2.30 |
2.98 |
|
YKAAG |
6.02
|
-0.50 |
4.78 |
|
LYKAA |
6.41
|
-1.30 |
3.98 |
P55196 |
YEPPS |
3.97
|
-3.71 |
1.57 |
|
PYLVE |
4.54
|
-2.15 |
3.13 |
|
ELYNN |
4.88
|
-2.80 |
2.48 |
P00519 |
YPAPK |
5.75
|
-1.48 |
3.80 |
|
VYGVS |
6.04
|
-1.68 |
3.60 |
O15455 |
YLCNT |
4.69
|
-1.29 |
3.99 |
|
SHYLC |
6.48
|
-1.08 |
4.20 |
Q13444 |
GSYVS |
6.40
|
-1.28 |
4.00 |
|
YVSCT |
6.42
|
-1.44 |
3.84 |
Q9Y5K6 |
SVYLS |
5.48
|
-2.60 |
2.68 |
|
CYSPK |
6.20
|
-1.78 |
3.50 |
P56945 |
YQVPG |
4.77
|
-2.85 |
2.43 |
|
YENSE |
5.37
|
-1.40 |
3.88 |
|
QYTPM |
5.62
|
-1.67 |
3.61 |
P07550 |
YSSNG |
6.25
|
-0.74 |
4.54 |
|
AYGNG |
6.41
|
0.13 |
5.41 |
P21860 |
YMPMN |
3.28
|
-3.49 |
1.79 |
|
YEYMN |
4.12
|
-3.24 |
2.04 |
|
YAAMG |
4.54
|
-2.31 |
2.97 |
|