ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1H3H2.PDB
Scoring matrix: 1H3H2_mat
Uniprot code: O89100
Genome source: Mus musculus
Wild-type ligand: APSIDRSTKPA
Foldx wt ligand score: 6.99
Foldx random average score for Mus musculus: 13.822

Available information for O89100 in MINT (Nov 2008):
Nš of interacting proteins: 14
 Proteins belonging to other specie: 8
Nš of interactions described: 28
 Interactions with other species: 14

Genome scanning information:
Subcellular location: False
Proteins in genome Mus musculus: 58346
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 13900
Total scanned proteins: 44446
 Total fragments: 20331123
Proteins after random average filtering: 44440
 Total fragments: 13950385
Proteins after disorder filtering: 31944
 Total fragments: 1136795
Proteins after pattern filtering: 22579
 Total fragments: 283359
Proteins after MINT filtering: 6
 Total fragments: 207


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

APSIDRSTKPA

6.99

-7.43

0.00

Best peptides

MPMMPRRLRRR

0.00

-6.19

1.24

         
Interactors      
Q9QUN3

VKGPPSVPRRD

8.02

-7.08

0.35

VPLPRFPEAGS

8.13

-6.85

0.58

APSPLPRAGKK

8.34

-6.09

1.34

P70218

PPLPPKPKFRS

7.53

-7.69

-0.26

SGPPPRTPRPG

8.48

-7.80

-0.37

PPKPKFRSPSD

8.96

-8.20

-0.77

Q80U87

EPVPSKLPTQM

8.92

-5.27

2.16

MYPPEMAPSSA

10.69

-4.38

3.05

LEEPVPSKLPT

11.01

-5.17

2.26

Q9Z1S8

PPRPPKPSQAE

8.50

-5.95

1.48

SPSPHRKPSTS

8.69

-6.87

0.56

IAPPPRPPKPS

10.02

-9.51

-2.08

O35601

PRFPRHTFGQK

7.76

-5.94

1.49

PPVPENELKPG

8.30

-6.98

0.45

TDSKPRFPRHT

8.45

-3.31

4.12

Q9QYY0

PNSPPRQHSGS

7.68

-7.98

-0.55

IPRTFPSDRSS

8.47

-6.73

0.70

RPPKPHPTHDR

8.87

-2.74

4.69

 


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