ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1GBR2.PDB
Scoring matrix: 1GBR2_mat
Uniprot code: Q60631
Genome source: Mus musculus
Wild-type ligand: LLPKLPPK
Foldx wt ligand score: 5.52
Foldx random average score for Mus musculus: 5.793

Available information for Q60631 in MINT (Nov 2008):
Nš of interacting proteins: 32
 Proteins belonging to other specie: 6
Nš of interactions described: 55
 Interactions with other species: 12

Genome scanning information:
Subcellular location: False
Proteins in genome Mus musculus: 58346
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 13900
Total scanned proteins: 44446
 Total fragments: 20464456
Proteins after random average filtering: 44444
 Total fragments: 10637107
Proteins after disorder filtering: 33007
 Total fragments: 1038416
Proteins after pattern filtering: 20797
 Total fragments: 118618
Proteins after MINT filtering: 24
 Total fragments: 197


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

LLPKLPPK

5.52

-3.75

0.00

Best peptides

FMGVDMRH

0.00

3.40

7.15

         
Interactors      
Q62245

LKSPGVRP

3.30

-1.67

2.08

YSYPLKSP

4.33

-1.43

2.32

GVRPSNPR

5.12

0.97

4.72

Q02384

LKSPGIRP

3.27

-1.67

2.08

SEEPLIPP

4.15

-1.63

2.12

DPLPDTPP

4.41

-0.29

3.46

P39054

GIPPGVPS

3.44

-1.27

2.48

IIRPAEPS

3.58

-0.95

2.80

PSRPGPQS

3.61

0.40

4.15

P35991

LKKPLPPE

4.94

-2.84

0.91

TKKPLPPT

5.20

-2.92

0.83

PPTPEEDQ

5.22

-0.82

2.93

Q9Z1S8

PMNPGSST

0.80

-1.85

1.90

PMSPGPHH

1.28

-2.03

1.72

DFQPGSPS

3.35

-0.26

3.49

Q62077

DGPDGMPV

3.89

0.16

3.91

GPDGMPVI

5.35

-1.72

2.03

WDGPDGMP

5.57

0.86

4.61

P70424

PIRPAGAT

3.24

-0.74

3.01

PCHPECQP

3.64

-0.25

3.50

PLTPEGPP

3.90

-2.34

1.41

Q8R550

PPKPGTMA

4.22

-0.19

3.56

PSVPAIPP

4.27

0.67

4.42

PVGPLTHT

4.31

-1.98

1.77

Q923U0

DLSPIVPV

4.67

-3.19

0.56

QISPNRPT

5.00

-1.46

2.29

PSAPSCDL

5.16

1.15

4.90

O35716

PAVPAPAP

4.51

0.49

4.24

SSSPAAPV

4.62

1.15

4.90

RPCPAVPA

5.69

0.87

4.62

Q80U87

EMAPSSAP

2.78

-1.90

1.85

LPTQMPPP

5.29

-1.69

2.06

PPEMAPSS

5.57

-0.03

3.72

Q61234

AAEPGAAP

3.16

0.29

4.04

DGEPGPEP

3.36

0.42

4.17

PSSPGPQP

3.59

0.45

4.20

Q9JLQ0

PKMPGRRL

3.22

-0.50

3.25

SEVPLTGP

4.18

-1.54

2.21

PSKPAAPQ

4.30

0.83

4.58

Q60749

PSTPGPDA

3.69

0.52

4.27

RASPATQP

4.64

0.61

4.36

APTPLLPP

5.05

-1.48

2.27

Q99JZ7

PLTPIKSC

4.41

-2.98

0.77

RVVPDPNP

4.51

-1.31

2.44

GSRPLPPL

4.58

-1.32

2.43

Q9QUN3

PATPLKTT

4.59

-1.54

2.21

SSLPAAPS

4.64

1.24

4.99

GKKPATPL

4.73

-0.04

3.71

P04925

WNKPSKPK

5.21

0.13

3.88

Q9WU78

PGYPGYCQ

2.45

0.21

3.96

PTYPGYPG

3.19

0.44

4.19

TMPPAKPQ

3.25

-2.00

1.75

Q60992

RGDPDSPW

2.86

-0.47

3.28

HGNPAPPG

4.22

0.41

4.16

PAPPGKPV

4.33

0.15

3.90

P98083

LGPKGEPG

3.71

0.09

3.84

PPLPGDDS

4.39

0.25

4.00

PPCPGREL

4.53

-0.25

3.50

Q9EQ32

ASAPGPPP

3.57

0.79

4.54

NLPPEISP

5.34

-2.58

1.17

PPPPDNEP

5.61

0.20

3.95

Q61824

PGIPGQSI

2.45

0.21

3.96

LWGPGAKP

3.21

-1.64

2.11

PIRPAPKH

3.38

-0.13

3.62

Q91ZZ2

ASKPDGQP

3.19

1.00

4.75

PPLPGIRV

3.78

-0.90

2.85

PSSPASKP

4.12

0.34

4.09

Q9QYY0

PMTPGTFD

1.58

-1.78

1.97

PMNPNLSG

3.28

-2.02

1.73

PMNPNSPP

3.31

-2.47

1.28

 


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