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Matrix information:
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ADAN-name: 1FYR2.PDB
Scoring matrix: 1FYR2_mat
Uniprot code: P62993
Genome source: Homo sapiens
Wild-type ligand: yVNV
Foldx wt ligand score: 1.3
Foldx random average score for Homo sapiens: 13.448 Available information for P62993 in MINT (Nov 2008):
Nš of interacting proteins: 64
Proteins belonging to other specie: 6
Nš of interactions described: 157
Interactions with other species: 28
Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
Total fragments: 22392853
Proteins after random average filtering: 48057
Total fragments: 12780715
Proteins after disorder filtering: 38199
Total fragments: 1075838
Proteins after pattern filtering: 19087
Total fragments: 87676
Proteins after MINT filtering: 33
Total fragments: 249
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
yVNV |
1.30
|
-12.89 |
0.00 |
| Best peptides |
yLNM |
0.00
|
-12.01 |
0.88 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P05067 |
FFYG |
10.20
|
1.00 |
13.89 |
|
TDYA |
11.27
|
-5.25 |
7.64 |
|
DYAD |
12.37
|
-2.98 |
9.91 |
| O43609 |
DSYS |
12.00
|
-2.55 |
10.34 |
|
YSDN |
12.00
|
-3.50 |
9.39 |
| Q07890 |
KTYK |
11.18
|
-3.17 |
9.72 |
|
TYKR |
12.43
|
-1.36 |
11.53 |
| P35968 |
SGYQ |
12.55
|
4.26 |
17.15 |
|
SGYH |
12.72
|
-0.98 |
11.91 |
| Q6S383 |
KAYS |
11.28
|
3.13 |
16.02 |
|
RRYA |
11.64
|
-4.24 |
8.65 |
|
SSYS |
12.38
|
-2.84 |
10.05 |
| O43561 |
YLVV |
10.66
|
-4.68 |
8.21 |
|
DDYH |
11.14
|
-4.29 |
8.60 |
|
PGYL |
11.24
|
-0.29 |
12.60 |
| Q13191 |
DEYK |
10.49
|
-5.86 |
7.03 |
|
EEYD |
10.54
|
-4.21 |
8.68 |
|
QDYD |
10.64
|
-6.18 |
6.71 |
| Q07912 |
ELYL |
8.79
|
1.25 |
14.14 |
|
YAFV |
9.92
|
1.97 |
14.86 |
|
YDDV |
10.61
|
-6.94 |
5.95 |
| Q15303 |
YWNH |
8.42
|
-6.89 |
6.00 |
|
YHNA |
8.50
|
-7.18 |
5.71 |
|
CIYY |
10.35
|
3.02 |
15.91 |
| P00533 |
YHNQ |
8.41
|
-6.21 |
6.68 |
|
MLYN |
9.02
|
0.58 |
13.47 |
|
PDYQ |
10.95
|
-7.01 |
5.88 |
| P62993 |
RNYV |
11.14
|
-4.27 |
8.62 |
|
NYVT |
12.64
|
-2.75 |
10.14 |
| P22681 |
TEYM |
10.15
|
-4.19 |
8.70 |
|
YDDD |
11.09
|
-6.40 |
6.49 |
|
PNYD |
11.33
|
-3.64 |
9.25 |
| P29353 |
YYND |
7.87
|
-6.97 |
5.92 |
|
QYYN |
10.84
|
1.24 |
14.13 |
|
YNDF |
11.67
|
-4.66 |
8.23 |
| Q13094 |
MYID |
9.63
|
-4.39 |
8.50 |
|
SMYI |
9.87
|
-1.21 |
11.68 |
|
YIDR |
10.45
|
-6.81 |
6.08 |
| Q13480 |
LYNL |
6.05
|
-7.76 |
5.13 |
|
ELYV |
9.18
|
-5.47 |
7.42 |
|
YVFN |
10.06
|
-2.56 |
10.33 |
| P08729 |
SLYG |
11.07
|
3.26 |
16.15 |
|
LYGL |
11.35
|
-2.27 |
10.62 |
| Q13905 |
YDNI |
6.84
|
-10.49 |
2.40 |
|
QYDN |
11.45
|
-3.59 |
9.30 |
|
SQYD |
11.73
|
-4.45 |
8.44 |
| P07949 |
YPND |
10.85
|
-7.09 |
5.80 |
|
LYGM |
11.12
|
-2.93 |
9.96 |
|
PGYL |
11.24
|
-0.29 |
12.60 |
| Q07889 |
KKYS |
11.01
|
-3.77 |
9.12 |
|
KTYK |
11.18
|
-3.17 |
9.72 |
|
KAYS |
11.28
|
3.13 |
16.02 |
| Q07666 |
EYYD |
10.56
|
-4.10 |
8.79 |
|
YDYG |
11.00
|
-5.56 |
7.33 |
|
YYDY |
11.22
|
-4.28 |
8.61 |
| Q9UKW4 |
VDYS |
11.23
|
-0.82 |
12.07 |
|
RNYS |
11.84
|
-3.19 |
9.70 |
| Q9UQC2 |
SVYI |
10.33
|
2.31 |
15.20 |
|
ENYV |
10.36
|
-4.43 |
8.46 |
|
DVYT |
10.71
|
-5.80 |
7.09 |
| P11137 |
YSNT |
8.44
|
-7.89 |
5.00 |
|
DDYL |
10.08
|
-6.14 |
6.75 |
|
TFYE |
11.23
|
7.95 |
20.84 |
| P48634 |
FLYS |
9.09
|
3.43 |
16.32 |
|
PLYL |
9.28
|
1.25 |
14.14 |
|
EYFA |
10.27
|
-3.49 |
9.40 |
| Q04695 |
YSFG |
11.43
|
1.14 |
14.03 |
|
SCYS |
11.70
|
-3.30 |
9.59 |
|
SSYS |
12.38
|
-2.84 |
10.05 |
| P27986 |
GYNE |
9.15
|
-5.63 |
7.26 |
|
NGYN |
12.49
|
-1.67 |
11.22 |
| Q13444 |
HCYC |
11.67
|
6.82 |
19.71 |
|
GSYV |
12.08
|
-2.91 |
9.98 |
|
CYCE |
12.21
|
-2.54 |
10.35 |
| P05787 |
LSYS |
10.59
|
1.80 |
14.69 |
|
RSYT |
11.90
|
-3.46 |
9.43 |
|
SAYG |
12.17
|
-3.51 |
9.38 |
| Q8WV28 |
ENYI |
9.94
|
-4.92 |
7.97 |
|
RDYA |
11.33
|
-3.23 |
9.66 |
|
NYIH |
11.34
|
-3.24 |
9.65 |
| P05783 |
SVYA |
11.36
|
3.12 |
16.01 |
|
PSYG |
12.27
|
-3.19 |
9.70 |
|
VYAG |
12.95
|
-2.33 |
10.56 |
| P13987 |
CYNC |
8.20
|
-6.31 |
6.58 |
|
QCYN |
10.87
|
-3.66 |
9.23 |
| P04626 |
YVNQ |
7.69
|
-7.07 |
5.82 |
|
LSYM |
9.27
|
-4.56 |
8.33 |
|
LYYW |
9.51
|
2.81 |
15.70 |
| P21860 |
YMNR |
7.07
|
-8.41 |
4.48 |
|
YEYM |
9.49
|
2.01 |
14.90 |
|
PIYK |
9.84
|
1.36 |
14.25 |
|
