ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1FYR2.PDB
Scoring matrix: 1FYR2_mat
Uniprot code: P62993
Genome source: Homo sapiens
Wild-type ligand: yVNV
Foldx wt ligand score: 1.3
Foldx random average score for Homo sapiens: 13.448

Available information for P62993 in MINT (Nov 2008):
Nš of interacting proteins: 64
 Proteins belonging to other specie: 6
Nš of interactions described: 157
 Interactions with other species: 28

Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
 Total fragments: 22392853
Proteins after random average filtering: 48057
 Total fragments: 12780715
Proteins after disorder filtering: 38199
 Total fragments: 1075838
Proteins after pattern filtering: 19087
 Total fragments: 87676
Proteins after MINT filtering: 33
 Total fragments: 249


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

yVNV

1.30

-12.89

0.00

Best peptides

yLNM

0.00

-12.01

0.88

         
Interactors      
P05067

FFYG

10.20

1.00

13.89

TDYA

11.27

-5.25

7.64

DYAD

12.37

-2.98

9.91

O43609

DSYS

12.00

-2.55

10.34

YSDN

12.00

-3.50

9.39

Q07890

KTYK

11.18

-3.17

9.72

TYKR

12.43

-1.36

11.53

P35968

SGYQ

12.55

4.26

17.15

SGYH

12.72

-0.98

11.91

Q6S383

KAYS

11.28

3.13

16.02

RRYA

11.64

-4.24

8.65

SSYS

12.38

-2.84

10.05

O43561

YLVV

10.66

-4.68

8.21

DDYH

11.14

-4.29

8.60

PGYL

11.24

-0.29

12.60

Q13191

DEYK

10.49

-5.86

7.03

EEYD

10.54

-4.21

8.68

QDYD

10.64

-6.18

6.71

Q07912

ELYL

8.79

1.25

14.14

YAFV

9.92

1.97

14.86

YDDV

10.61

-6.94

5.95

Q15303

YWNH

8.42

-6.89

6.00

YHNA

8.50

-7.18

5.71

CIYY

10.35

3.02

15.91

P00533

YHNQ

8.41

-6.21

6.68

MLYN

9.02

0.58

13.47

PDYQ

10.95

-7.01

5.88

P62993

RNYV

11.14

-4.27

8.62

NYVT

12.64

-2.75

10.14

P22681

TEYM

10.15

-4.19

8.70

YDDD

11.09

-6.40

6.49

PNYD

11.33

-3.64

9.25

P29353

YYND

7.87

-6.97

5.92

QYYN

10.84

1.24

14.13

YNDF

11.67

-4.66

8.23

Q13094

MYID

9.63

-4.39

8.50

SMYI

9.87

-1.21

11.68

YIDR

10.45

-6.81

6.08

Q13480

LYNL

6.05

-7.76

5.13

ELYV

9.18

-5.47

7.42

YVFN

10.06

-2.56

10.33

P08729

SLYG

11.07

3.26

16.15

LYGL

11.35

-2.27

10.62

Q13905

YDNI

6.84

-10.49

2.40

QYDN

11.45

-3.59

9.30

SQYD

11.73

-4.45

8.44

P07949

YPND

10.85

-7.09

5.80

LYGM

11.12

-2.93

9.96

PGYL

11.24

-0.29

12.60

Q07889

KKYS

11.01

-3.77

9.12

KTYK

11.18

-3.17

9.72

KAYS

11.28

3.13

16.02

Q07666

EYYD

10.56

-4.10

8.79

YDYG

11.00

-5.56

7.33

YYDY

11.22

-4.28

8.61

Q9UKW4

VDYS

11.23

-0.82

12.07

RNYS

11.84

-3.19

9.70

Q9UQC2

SVYI

10.33

2.31

15.20

ENYV

10.36

-4.43

8.46

DVYT

10.71

-5.80

7.09

P11137

YSNT

8.44

-7.89

5.00

DDYL

10.08

-6.14

6.75

TFYE

11.23

7.95

20.84

P48634

FLYS

9.09

3.43

16.32

PLYL

9.28

1.25

14.14

EYFA

10.27

-3.49

9.40

Q04695

YSFG

11.43

1.14

14.03

SCYS

11.70

-3.30

9.59

SSYS

12.38

-2.84

10.05

P27986

GYNE

9.15

-5.63

7.26

NGYN

12.49

-1.67

11.22

Q13444

HCYC

11.67

6.82

19.71

GSYV

12.08

-2.91

9.98

CYCE

12.21

-2.54

10.35

P05787

LSYS

10.59

1.80

14.69

RSYT

11.90

-3.46

9.43

SAYG

12.17

-3.51

9.38

Q8WV28

ENYI

9.94

-4.92

7.97

RDYA

11.33

-3.23

9.66

NYIH

11.34

-3.24

9.65

P05783

SVYA

11.36

3.12

16.01

PSYG

12.27

-3.19

9.70

VYAG

12.95

-2.33

10.56

P13987

CYNC

8.20

-6.31

6.58

QCYN

10.87

-3.66

9.23

P04626

YVNQ

7.69

-7.07

5.82

LSYM

9.27

-4.56

8.33

LYYW

9.51

2.81

15.70

P21860

YMNR

7.07

-8.41

4.48

YEYM

9.49

2.01

14.90

PIYK

9.84

1.36

14.25

 


    Comments or questions on the site? Send a mail to adandatabase@umh.es                                                     
DISCLAIMER