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Matrix information:
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ADAN-name: 1CWD2.PDB
Scoring matrix: 1CWD2_mat
Uniprot code: P06239
Genome source: Homo sapiens
Wild-type ligand: EGDyEEVL
Foldx wt ligand score: 4.1
Foldx random average score for Homo sapiens: 19.467 Available information for P06239 in MINT (Nov 2008):
Nš of interacting proteins: 20
Proteins belonging to other specie: 3
Nš of interactions described: 50
Interactions with other species: 22
Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
Total fragments: 22200620
Proteins after random average filtering: 48046
Total fragments: 11414554
Proteins after disorder filtering: 36271
Total fragments: 1028269
Proteins after pattern filtering: 18367
Total fragments: 112578
Proteins after MINT filtering: 10
Total fragments: 70
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
EGDyEEVL |
4.10
|
-10.01 |
0.00 |
| Best peptides |
yGsyDEDG |
0.00
|
-7.96 |
2.05 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P20963 |
KGHDGLYQ |
15.06
|
-0.23 |
9.78 |
|
GHDGLYQG |
17.65
|
-1.63 |
8.38 |
| P04150 |
NGYSSPSM |
17.31
|
0.81 |
10.82 |
| P27986 |
NGYNETTG |
16.32
|
-2.82 |
7.19 |
|
YNETTGER |
16.39
|
-0.40 |
9.61 |
| P22681 |
DGYDVPKP |
11.69
|
-4.40 |
5.61 |
|
YDDDDDER |
12.08
|
-6.28 |
3.73 |
|
EDDGYDVP |
13.59
|
-4.86 |
5.15 |
| Q07666 |
YGQDDWNG |
10.66
|
-5.59 |
4.42 |
|
QGDSEYYD |
13.87
|
-3.02 |
6.99 |
|
DSEYYDYG |
14.34
|
-2.89 |
7.12 |
| Q13283 |
NSSYVHGG |
17.79
|
-2.92 |
7.09 |
|
KNSSYVHG |
19.44
|
0.32 |
10.33 |
| Q13444 |
SGSYVSCT |
14.13
|
-4.43 |
5.58 |
|
YCEEGWAP |
15.48
|
-4.20 |
5.81 |
|
HCYCEEGW |
18.75
|
-0.78 |
9.23 |
| Q13094 |
DGDYESPN |
11.04
|
-4.51 |
5.50 |
|
EDDADYEP |
12.52
|
-6.30 |
3.71 |
|
FEEDDYES |
13.31
|
-5.17 |
4.84 |
| Q12959 |
DGYAPPDI |
14.77
|
-0.79 |
9.22 |
|
MNDGYAPP |
16.92
|
-1.35 |
8.66 |
|
NDGYAPPD |
17.34
|
-5.21 |
4.80 |
| P43403 |
MDTSVYES |
15.39
|
-5.28 |
4.73 |
|
DGYTPEPA |
16.30
|
0.15 |
10.16 |
|
SDGYTPEP |
17.11
|
-2.93 |
7.08 |
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