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Matrix information:
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ADAN-name: 1BMB2.PDB
Scoring matrix: 1BMB2_mat
Uniprot code: P62993
Genome source: Homo sapiens
Wild-type ligand: KPFyVNVEF
Foldx wt ligand score: 5.57
Foldx random average score for Homo sapiens: 18.796 Available information for P62993 in MINT (Nov 2008):
Nš of interacting proteins: 64
Proteins belonging to other specie: 6
Nš of interactions described: 157
Interactions with other species: 28
Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
Total fragments: 22152566
Proteins after random average filtering: 48040
Total fragments: 11235003
Proteins after disorder filtering: 34964
Total fragments: 718170
Proteins after pattern filtering: 17692
Total fragments: 101254
Proteins after MINT filtering: 32
Total fragments: 344
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
KPFyVNVEF |
5.57
|
-17.97 |
0.00 |
| Best peptides |
MyDyyNLss |
0.00
|
-18.89 |
-0.92 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P05067 |
GGADTDYAD |
15.96
|
-3.03 |
14.94 |
|
CAPFFYGGC |
17.17
|
1.09 |
19.06 |
|
PFFYGGCGG |
17.80
|
-5.25 |
12.72 |
| O43609 |
NDDEGDSYS |
14.31
|
-3.48 |
14.49 |
|
SYSDNPCSC |
16.32
|
-6.21 |
11.76 |
|
GDSYSDNPC |
16.74
|
-7.96 |
10.01 |
| Q07890 |
KLPPKTYKR |
17.80
|
-5.63 |
12.34 |
| P35968 |
SGYHSDDTD |
17.74
|
-3.27 |
14.70 |
| Q6S383 |
YSPYSVSGS |
17.20
|
-3.87 |
14.10 |
|
YYSPYSVSG |
17.81
|
-3.38 |
14.59 |
|
YSDPSTGEP |
18.20
|
-5.45 |
12.52 |
| O43561 |
DEDEDDYHN |
12.47
|
-6.12 |
11.85 |
|
PGYLVVLPD |
14.39
|
-6.82 |
11.15 |
|
ADEDEDDYH |
14.52
|
-6.36 |
11.61 |
| Q13191 |
GSEEYDVPP |
12.62
|
-5.13 |
12.84 |
|
PSDYDLLIP |
12.76
|
-7.72 |
10.25 |
|
SDYDLLIPP |
13.17
|
-9.33 |
8.64 |
| Q07912 |
DRIDELYLG |
13.42
|
-6.36 |
11.61 |
|
RIDELYLGN |
13.76
|
1.76 |
19.73 |
|
IDELYLGNP |
14.39
|
-6.91 |
11.06 |
| Q15303 |
NPDYWNHSL |
11.65
|
-9.68 |
8.29 |
|
NPEYHNASN |
13.55
|
-7.82 |
10.15 |
|
ELDEEGYMT |
14.48
|
-5.38 |
12.59 |
| P00533 |
CPPLMLYNP |
13.75
|
-6.36 |
11.61 |
|
NPVYHNQPL |
14.25
|
-8.91 |
9.06 |
|
TCPPLMLYN |
14.82
|
-7.50 |
10.47 |
| P62993 |
GMFPRNYVT |
14.50
|
-9.40 |
8.57 |
|
FPRNYVTPV |
17.57
|
-5.40 |
12.57 |
|
MFPRNYVTP |
18.08
|
2.17 |
20.14 |
| P22681 |
EDTEYMTPS |
13.13
|
-6.49 |
11.48 |
|
SENEDDGYD |
13.91
|
-2.91 |
15.06 |
|
NYDDDDDER |
13.99
|
-2.46 |
15.51 |
| P29353 |
DHQYYNDFP |
13.29
|
-8.01 |
9.96 |
|
YYNDFPGKE |
15.54
|
-5.84 |
12.13 |
|
HQYYNDFPG |
16.26
|
-7.25 |
10.72 |
| Q13094 |
SFEEDDYES |
11.79
|
-6.10 |
11.87 |
|
VEDDADYEP |
13.85
|
-3.15 |
14.82 |
|
GEDDGDYES |
14.39
|
-8.30 |
9.67 |
| Q13480 |
HDSEENYVP |
12.05
|
-7.08 |
10.89 |
|
PPPYQLINV |
13.15
|
-9.63 |
8.34 |
|
ELYVFNTPS |
13.95
|
-9.89 |
8.08 |
| P08729 |
LGSSSLYGL |
16.89
|
-4.50 |
13.47 |
| Q13905 |
PSQYDNISG |
13.86
|
-8.91 |
9.06 |
|
QYDNISGED |
16.57
|
-3.09 |
14.88 |
|
SQYDNISGE |
16.74
|
-6.06 |
11.91 |
| P07949 |
VGPGYLGSG |
16.92
|
-3.49 |
14.48 |
|
FPRYPNDSV |
17.43
|
-5.44 |
12.53 |
|
KAGYGTCNC |
17.44
|
-3.72 |
14.25 |
| Q07889 |
YKREHTHPS |
15.93
|
-3.48 |
14.49 |
|
KYSYPLKSP |
16.53
|
-6.80 |
11.17 |
|
KKYSYPLKS |
17.29
|
-3.65 |
14.32 |
| Q07666 |
YGQDDWNGT |
15.99
|
3.35 |
21.32 |
|
GDSEYYDYG |
16.77
|
1.52 |
19.49 |
|
PPAPETYEE |
17.27
|
-3.75 |
14.22 |
| Q9UQC2 |
GDSEENYVP |
11.85
|
-6.59 |
11.38 |
|
TNSEDNYVP |
12.69
|
-6.07 |
11.90 |
|
ETDNEDVYT |
14.67
|
-5.08 |
12.89 |
| P11137 |
SMDEGDDYL |
13.23
|
-3.69 |
14.28 |
|
QGTYSNTKE |
14.74
|
-9.62 |
8.35 |
|
GDDYLPATT |
16.20
|
-6.42 |
11.55 |
| P48634 |
MMPPFMYPP |
14.61
|
-7.14 |
10.83 |
|
PPPSFLYSP |
14.95
|
-6.04 |
11.93 |
|
PPPKALYPG |
15.58
|
-5.76 |
12.21 |
| Q04695 |
CYSFGSGGG |
18.29
|
-2.95 |
15.02 |
| P27986 |
GYNETTGER |
14.98
|
-2.75 |
15.22 |
|
NGYNETTGE |
18.20
|
-3.67 |
14.30 |
| O43597 |
KCKECTYPR |
15.42
|
-4.47 |
13.50 |
|
CTYPRPLPS |
17.73
|
-4.11 |
13.86 |
| Q13444 |
YCEEGWAPP |
14.02
|
3.45 |
21.42 |
|
CYCEEGWAP |
15.84
|
-1.87 |
16.10 |
|
SGSYVSCTP |
17.65
|
-3.93 |
14.04 |
| P05787 |
GLSYSLGSS |
15.24
|
-6.47 |
11.50 |
|
GYAGGLSSA |
17.36
|
-3.40 |
14.57 |
|
LTSPGLSYS |
17.57
|
-4.08 |
13.89 |
| Q8WV28 |
DDFDSDYEN |
15.60
|
-4.64 |
13.33 |
|
SDYENPDEH |
16.04
|
-4.73 |
13.24 |
|
DSDYENPDE |
16.79
|
-7.12 |
10.85 |
| P13987 |
SLQCYNCPN |
14.06
|
-8.91 |
9.06 |
| P04626 |
QPEYVNQPD |
11.89
|
-10.12 |
7.85 |
|
SPAFDNLYY |
12.26
|
-9.59 |
8.38 |
|
PQPEYVNQP |
13.76
|
-3.86 |
14.11 |
| P21860 |
DYEYMNRQR |
11.57
|
-11.07 |
6.90 |
|
EEEDVNGYV |
11.77
|
-5.45 |
12.52 |
|
GYMPMNQGN |
12.97
|
-9.00 |
8.97 |
|
