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Matrix information:
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ADAN-name: 1BHF2.PDB
Scoring matrix: 1BHF2_mat
Uniprot code: P06239
Genome source: Homo sapiens
Wild-type ligand: FEEI
Foldx wt ligand score: 3.21
Foldx random average score for Homo sapiens: 7.890 Available information for P06239 in MINT (Nov 2008):
Nš of interacting proteins: 20
Proteins belonging to other specie: 3
Nš of interactions described: 50
Interactions with other species: 22
Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
Total fragments: 22392853
Proteins after random average filtering: 48059
Total fragments: 11063145
Proteins after disorder filtering: 38024
Total fragments: 1308004
Proteins after pattern filtering: 17399
Total fragments: 60546
Proteins after MINT filtering: 9
Total fragments: 40
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
FEEI |
3.21
|
-7.02 |
0.00 |
| Best peptides |
FDsM |
0.00
|
-7.57 |
-0.55 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P04150 |
YSSP |
7.14
|
-3.31 |
3.71 |
| P27986 |
GYNE |
6.77
|
-4.41 |
2.61 |
| P22681 |
TEYM |
3.25
|
-6.59 |
0.43 |
|
YDVP |
5.05
|
-6.27 |
0.75 |
|
YDDD |
5.17
|
-4.15 |
2.87 |
| Q07666 |
TYEE |
5.86
|
-4.23 |
2.79 |
|
ETYE |
6.01
|
-3.23 |
3.79 |
|
YDYG |
6.21
|
-4.59 |
2.43 |
| Q13444 |
YCEE |
5.90
|
-2.54 |
4.48 |
|
CYCE |
6.46
|
-1.16 |
5.86 |
|
YVSC |
7.40
|
-3.68 |
3.34 |
| Q13094 |
DDYE |
2.03
|
-6.56 |
0.46 |
|
GDYE |
4.32
|
-4.65 |
2.37 |
|
ADYE |
4.34
|
-5.90 |
1.12 |
| Q12959 |
MYMN |
6.73
|
-4.03 |
2.99 |
|
YMND |
7.11
|
-2.82 |
4.20 |
|
DGYA |
7.12
|
-2.80 |
4.22 |
| P43405 |
YDVV |
6.17
|
-4.80 |
2.22 |
|
YSFP |
6.86
|
-3.83 |
3.19 |
| P43403 |
YESP |
5.35
|
-5.67 |
1.35 |
|
SVYE |
6.12
|
-2.78 |
4.24 |
|
YTPE |
7.25
|
-2.75 |
4.27 |
|
