ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1B8Q2.PDB
Scoring matrix: 1B8Q2_mat
Uniprot code: P29476
Genome source: Rattus norvegicus
Wild-type ligand: VVKVDSV
Foldx wt ligand score: 5.59
Foldx random average score for Rattus norvegicus: 10.896

Available information for P29476 in MINT (Nov 2008):
Nš of interacting proteins: 14
 Proteins belonging to other specie: 3
Nš of interactions described: 28
 Interactions with other species: 7

Genome scanning information:
Subcellular location: False
Proteins in genome Rattus norvegicus: 15006
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 3052
Total scanned proteins: 11954
 Total fragments: 5580843
Proteins after random average filtering: 11954
 Total fragments: 3591954
Proteins after disorder filtering: 9311
 Total fragments: 367622
Proteins after pattern filtering: 6971
 Total fragments: 33485
Proteins after MINT filtering: 9
 Total fragments: 32


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

VVKVDSV

5.59

-4.76

0.00

Best peptides

RRFDMDV

0.00

7.50

12.26

         
Interactors      
O54960

SHIDTTV

5.28

-6.02

-1.26

LGTGTPL

8.43

-4.51

0.25

Q9Z2F5

PPGVVSV

4.93

-5.60

-0.84

PGVVSVA

8.79

-3.19

1.57

Q63622

DKFGSCV

5.31

-4.59

0.17

PHYHLGL

7.45

-5.74

-0.98

LEYKTSL

8.32

-5.52

-0.76

Q80W92

DGPDLQV

3.77

-6.44

-1.68

FGSGISV

5.81

-4.95

-0.19

DEPKSVA

9.83

-3.22

1.54

P97756

ASRPTPV

4.72

-6.34

-1.58

RARAASV

5.53

-5.11

-0.35

PPRGSQA

7.24

-2.43

2.33

Q00960

VVGGVPA

5.50

-4.16

0.60

HNYSSTV

6.50

-4.40

0.36

SKKPLDI

6.90

-9.20

-4.44

P47858

GQGGSKL

9.34

-3.73

1.03

P31016

DKFGSCV

5.31

-4.59

0.17

NSPPVIV

6.51

-7.82

-3.06

YLSDSYA

7.43

-1.95

2.81

P63331

DRGGWGI

8.97

-5.58

-0.82

 


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