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Matrix information:
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ADAN-name: 1AOU2.PDB
Scoring matrix: 1AOU2_mat
Uniprot code: P06241
Genome source: Homo sapiens
Wild-type ligand: EPQyEEIPIYL
Foldx wt ligand score: 19.34
Foldx random average score for Homo sapiens: 12.797 Available information for P06241 in MINT (Nov 2008):
Nš of interacting proteins: 29
Proteins belonging to other specie: 8
Nš of interactions described: 52
Interactions with other species: 15
Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
Total fragments: 22056464
Proteins after random average filtering: 48040
Total fragments: 12191245
Proteins after disorder filtering: 35466
Total fragments: 1429178
Proteins after pattern filtering: 19389
Total fragments: 192644
Proteins after MINT filtering: 12
Total fragments: 149
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
EPQyEEIPIYL |
19.34
|
-2.58 |
0.00 |
| Best peptides |
syGDDyGDssp |
0.00
|
14.51 |
17.09 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P54253 |
PSPSDYSSRDP |
7.34
|
-2.89 |
-0.31 |
|
YGAPSSADLGL |
7.63
|
-1.78 |
0.80 |
|
VHPSPSDYSSR |
7.81
|
-1.37 |
1.21 |
| P11137 |
DEGDDYLPATT |
5.97
|
-3.32 |
-0.74 |
|
GEHGSQGTYSN |
6.41
|
1.71 |
4.29 |
|
YSNTKENGING |
7.36
|
-1.85 |
0.73 |
| O15117 |
DIYDGIEEEDA |
5.18
|
-3.20 |
-0.62 |
|
EVYDDVDTSDF |
5.33
|
-3.77 |
-1.19 |
|
PPPDDDIYDGI |
5.44
|
-3.02 |
-0.44 |
| P22681 |
SENEDDGYDVP |
3.94
|
-4.43 |
-1.85 |
|
EGEEDTEYMTP |
5.70
|
-2.77 |
-0.19 |
|
ENEDDGYDVPK |
5.88
|
-4.91 |
-2.33 |
| Q07666 |
YGQDDWNGTRP |
5.59
|
-3.34 |
-0.76 |
|
SQGDSEYYDYG |
5.94
|
-2.55 |
0.03 |
|
QSQGDSEYYDY |
6.09
|
-3.51 |
-0.93 |
| Q13283 |
KNSSYVHGGLD |
8.07
|
-1.42 |
1.16 |
|
YVHGGLDSNGK |
8.64
|
0.46 |
3.04 |
|
SYVHGGLDSNG |
9.64
|
0.16 |
2.74 |
| Q13444 |
CGRNPSGSYVS |
6.60
|
-0.60 |
1.98 |
|
NRHCYCEEGWA |
7.81
|
-1.24 |
1.34 |
|
GVCDSNRHCYC |
7.84
|
-1.21 |
1.37 |
| P42768 |
ITSSRYRGLPA |
9.92
|
-0.55 |
2.03 |
|
RYRGLPAPGPS |
10.95
|
-0.80 |
1.78 |
| P16333 |
WRGSYNGQVGW |
5.84
|
-0.40 |
2.18 |
|
GSYNGQVGWFP |
7.11
|
0.00 |
2.58 |
|
EPSPPQCDYIR |
7.66
|
-2.39 |
0.19 |
| Q9Y5K6 |
PKPSVYLSTPS |
8.48
|
-1.26 |
1.32 |
|
CYSPKPSVYLS |
9.07
|
-0.15 |
2.43 |
|
LLRSSGTVYPK |
9.33
|
0.60 |
3.18 |
| P29353 |
YYNDFPGKEPP |
5.79
|
-1.28 |
1.30 |
|
EPPDHQYYNDF |
7.18
|
-2.11 |
0.47 |
|
EEEPPDHQYYN |
8.03
|
-2.87 |
-0.29 |
| P35968 |
QTSGYQSGYHS |
8.50
|
-0.22 |
2.36 |
|
SNQTSGYQSGY |
8.54
|
-0.68 |
1.90 |
|
GYQSGYHSDDT |
8.69
|
-1.17 |
1.41 |
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