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Matrix information:
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ADAN-name: 1AD52.PDB
Scoring matrix: 1AD52_mat
Uniprot code: P08631
Genome source: Homo sapiens
Wild-type ligand: SKPQKPWEKD
Foldx wt ligand score: 5.34
Foldx random average score for Homo sapiens: 9.773 Available information for P08631 in MINT (Nov 2008):
Nš of interacting proteins: 16
Proteins belonging to other specie: 7
Nš of interactions described: 37
Interactions with other species: 17
Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
Total fragments: 22104514
Proteins after random average filtering: 48032
Total fragments: 10573304
Proteins after disorder filtering: 34341
Total fragments: 682579
Proteins after pattern filtering: 24384
Total fragments: 255017
Proteins after MINT filtering: 7
Total fragments: 213
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
SKPQKPWEKD |
5.34
|
-9.43 |
0.00 |
| Best peptides |
RRPHFPDMWK |
0.00
|
-9.58 |
-0.15 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q92556 |
APPPIPKEPS |
6.81
|
-8.91 |
0.52 |
|
QIPDAPPPIP |
7.92
|
-8.47 |
0.96 |
|
IPDAPPPIPK |
8.60
|
-7.82 |
1.61 |
| Q53H12 |
ERPPNEPEET |
6.59
|
-8.34 |
1.09 |
|
PTERPPNEPE |
8.21
|
-7.88 |
1.55 |
|
RPPNEPEETP |
9.30
|
-6.23 |
3.20 |
| Q13177 |
SLKPLPSVPE |
6.55
|
-9.48 |
-0.05 |
|
DKPPAPPVRM |
7.02
|
-8.94 |
0.49 |
|
KPPAPPVRMS |
7.13
|
-8.12 |
1.31 |
| O43516 |
PRPPLPPDRP |
4.67
|
-12.65 |
-3.22 |
|
NRPPLPPTPS |
4.90
|
-12.50 |
-3.07 |
|
SRPPLLPPGG |
5.42
|
-9.90 |
-0.47 |
| P42768 |
PRPPIVGGNK |
5.17
|
-11.26 |
-1.83 |
|
RRGGLPPLPL |
5.38
|
-11.04 |
-1.61 |
|
DRRQLPPPPT |
5.50
|
-11.27 |
-1.84 |
| P21860 |
PHPPRPSSLE |
5.06
|
-10.33 |
-0.90 |
|
RRHSPPHPPR |
6.27
|
-9.22 |
0.21 |
|
PLHPVPIMPT |
6.81
|
-8.04 |
1.39 |
| Q13444 |
PRKPLPADPQ |
4.25
|
-11.85 |
-2.42 |
|
ERPGPPQRAL |
5.79
|
-9.50 |
-0.07 |
|
SRPAPPPPTV |
5.93
|
-10.85 |
-1.42 |
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