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Matrix information:
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ADAN-name: 1A812.PDB
Scoring matrix: 1A812_mat
Uniprot code: P43405
Genome source: Homo sapiens
Wild-type ligand: QRDLySGLN
Foldx wt ligand score: 9.87
Foldx random average score for Homo sapiens: 13.877 Available information for P43405 in MINT (Nov 2008):
Nš of interacting proteins: 12
Proteins belonging to other specie: 1
Nš of interactions described: 40
Interactions with other species: 1
Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
Total fragments: 22152566
Proteins after random average filtering: 48043
Total fragments: 11585431
Proteins after disorder filtering: 35751
Total fragments: 1050792
Proteins after pattern filtering: 18719
Total fragments: 132867
Proteins after MINT filtering: 10
Total fragments: 128
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
QRDLySGLN |
9.87
|
-6.05 |
0.00 |
| Best peptides |
EyYyyDMMG |
0.00
|
-4.44 |
1.61 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P00533 |
CTYGCTGPG |
10.60
|
-1.47 |
4.58 |
|
YNPTTYQMD |
10.61
|
-2.77 |
3.28 |
|
NPEGKYSFG |
11.43
|
-0.87 |
5.18 |
| P27986 |
YNETTGERG |
12.43
|
-0.72 |
5.33 |
|
NGYNETTGE |
13.04
|
-0.62 |
5.43 |
| P22681 |
PNYDDDDDE |
9.02
|
-6.18 |
-0.13 |
|
GEEDTEYMT |
9.24
|
-6.77 |
-0.72 |
|
SENEDDGYD |
10.01
|
-4.34 |
1.71 |
| P04626 |
PEYLTPQGG |
10.50
|
-2.73 |
3.32 |
|
LPSETDGYV |
11.00
|
-1.87 |
4.18 |
|
QRYSEDPTV |
11.17
|
-3.81 |
2.24 |
| P21860 |
PGGDYAAMG |
9.54
|
-4.24 |
1.81 |
|
PDEDYEYMN |
9.76
|
-8.26 |
-2.21 |
|
SGYMPMNQG |
10.71
|
-2.43 |
3.62 |
| P06239 |
TYEGSNPPA |
12.94
|
-2.54 |
3.51 |
|
YPIVPLDGK |
13.40
|
-0.34 |
5.71 |
|
PLVTYEGSN |
13.85
|
-1.81 |
4.24 |
| P09769 |
SYGAADHYG |
10.59
|
-1.48 |
4.57 |
|
DHYGPDPTK |
11.16
|
-3.38 |
2.67 |
|
GAADHYGPD |
11.58
|
-2.04 |
4.01 |
| Q8WV28 |
FDSDYENPD |
10.94
|
-4.53 |
1.52 |
|
DYENPDEHS |
11.80
|
-2.35 |
3.70 |
|
DDFDSDYEN |
12.27
|
-3.42 |
2.63 |
| O00459 |
SHYRPELPA |
10.84
|
-4.09 |
1.96 |
|
YRPELPAPR |
12.41
|
-4.19 |
1.86 |
| Q15303 |
GELDEEGYM |
10.23
|
-3.61 |
2.44 |
|
GPYVSDCCH |
10.83
|
-2.61 |
3.44 |
|
PPAYTPMSG |
11.27
|
0.33 |
6.38 |
|
