INTERNAL ADAN INFORMATION

• Record: 849
• Number: 14
• Inclusion date: 5-I-2006

WHOLE PROTEIN INFORMATION

• Domains within protein: PTN6_HUMAN by SMART
• Basic UniProtKB Entry: PTN6_HUMAN
• InterPro link: PTN6_HUMAN
• Swiss-Prot ENTRY: PTN6_HUMAN
• Swiss-Prot AC number: P29350
• Sequence: P29350
• Pfam database: PTN6_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: P29350
• BLAST for whole protein: P29350
• SAS for whole protein: P29350
• BLAST for modular domain: 2B3O
• SAS for domain: 2B3O

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: SH2
• PsiBase: 2B3O
• MINT: whole protein: P29350 or domain: 2B3O
• DOMINO database: P29350
• APID: P29350

• Title: Crystal structure of human tyrosine phosphatase shp-1
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 2.8
• Protein Source: Homo sapiens
• Reference: Yang et al. 2003 J Biol Chem 278, 6516
• Sequence domain: seqA_2b3o2.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 2b3o
• Drugs:
• Phosphorylated residue type:
• Pfam family: SH2
• Pfam structure: 2B3O
• RCSB_PDB_ID: 2B3O
• SMART: SH2
• PDBsum (domain): 2B3O
• PDBsum (Ligand): 2B3O
• MSD (summary): 2B3O
• MSD (ligands): 2B3O
• Molecular Surface: 2b3o

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.