INTERNAL ADAN INFORMATION

• Record: 848
• Number: 13
• Inclusion date: 5-I-2006

WHOLE PROTEIN INFORMATION

• Domains within protein: GRB14_HUMAN by SMART
• Basic UniProtKB Entry: GRB14_HUMAN
• InterPro link: GRB14_HUMAN
• Swiss-Prot ENTRY: GRB14_HUMAN
• Swiss-Prot AC number: Q14449
• Sequence: Q14449
• Pfam database: GRB14_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: Q14449
• BLAST for whole protein: Q14449
• SAS for whole protein: Q14449
• BLAST for modular domain: 2AUG
• SAS for domain: 2AUG

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: SH2
• PsiBase: 2AUG
• MINT: whole protein: Q14449 or domain: 2AUG
• DOMINO database: Q14449
• APID: Q14449

• Title: Crystal structure of the grb14 sh2 domain
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 2.3
• Protein Source: Homo sapiens
• Reference: Depetris et al. 2005 Mol Cell 20, 325
• Sequence domain: seqA_2aug2.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 2aug
• Drugs:
• Phosphorylated residue type:
• Pfam family: SH2
• Pfam structure: 2AUG
• RCSB_PDB_ID: 2AUG
• SMART: SH2
• PDBsum (domain): 2AUG
• PDBsum (Ligand): 2AUG
• MSD (summary): 2AUG
• MSD (ligands): 2AUG
• Molecular Surface: 2aug

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.