INTERNAL ADAN INFORMATION

• Record: 85
• Number: 122
• Inclusion date: 21-VIII-2004

WHOLE PROTEIN INFORMATION

• Domains within protein: ABL2_HUMAN by SMART
• Basic UniProtKB Entry: ABL2_HUMAN
• InterPro link: ABL2_HUMAN
• Swiss-Prot ENTRY: ABL2_HUMAN
• Swiss-Prot AC number: P42684
• Sequence: P42684
• Pfam database: ABL2_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: P42684
• BLAST for whole protein: P42684
• SAS for whole protein: P42684
• BLAST for modular domain: 1OPL
• SAS for domain: 1OPL

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: 1OPL3_mat 
• iPfam: SH3
• PsiBase: 1OPL
• MINT: whole protein: P42684 or domain: 1OPL
• DOMINO database: P42684
• APID: P42684

• Title: STRUCTURAL BASIS FOR THE AUTO-INHIBITION OF C-ABL TYROSINE KINASE
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 3.42
• Protein Source: Homo sapiens
• Reference: Nagar et al. 2003 Cell 112, 859
• Sequence domain: seqA_1opl2.txt
• Peptide sequence of ligand: KPTVYGVSPN
• Biochemical affinity data for: 1opl
• Drugs:
• Phosphorylated residue type: n/a
• Pfam family: SH3
• Pfam structure: 1OPL
• RCSB_PDB_ID: 1OPL
• SMART: SH3
• PDBsum (domain): 1OPL
• PDBsum (Ligand): 1OPL
• MSD (summary): 1OPL
• MSD (ligands): 1OPL
• Molecular Surface: 1opl

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.