INTERNAL ADAN INFORMATION

• Record: 740
• Number: 19
• Inclusion date: 21-VI-2005

WHOLE PROTEIN INFORMATION

• Domains within protein: VHL_HUMAN by SMART
• Basic UniProtKB Entry: VHL_HUMAN
• InterPro link: VHL_HUMAN
• Swiss-Prot ENTRY: VHL_HUMAN
• Swiss-Prot AC number: P40337
• Sequence: P40337
• Pfam database: VHL_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: P40337
• BLAST for whole protein: P40337
• SAS for whole protein: P40337
• BLAST for modular domain: 1LM8
• SAS for domain: 1LM8

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: UBQ
• PsiBase: 1LM8
• MINT: whole protein: P40337 or domain: 1LM8
• DOMINO database: P40337
• APID: P40337

• Title: STRUCTURE OF A HIF-1A-PVHL-ELONGINB-ELONGINC COMPLEX
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 1.85
• Protein Source: Homo sapiens
• Reference: Min et al. 2002 Science 296, 1886-1889
• Sequence domain: seqA_1lm82.txt
• Peptide sequence of ligand: MLAXYIPMDDDFQLR
• Biochemical affinity data for: 1LM8
• Drugs:
• Phosphorylated residue type:
• Pfam family: UBQ
• Pfam structure: 1LM8
• RCSB_PDB_ID: 1LM8
• SMART: UBQ
• PDBsum (domain): 1LM8
• PDBsum (Ligand): 1LM8
• MSD (summary): 1LM8
• MSD (ligands): 1LM8
• Molecular Surface: 1LM8

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.