INTERNAL ADAN INFORMATION

• Record: 648
• Number: 8
• Inclusion date: 22-III-2005

WHOLE PROTEIN INFORMATION

• Domains within protein: PTN1_HUMAN by SMART
• Basic UniProtKB Entry: PTN1_HUMAN
• InterPro link: PTN1_HUMAN
• Swiss-Prot ENTRY: PTN1_HUMAN
• Swiss-Prot AC number: P18031
• Sequence: P18031
• Pfam database: PTN1_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: P18031
• BLAST for whole protein: P18031
• SAS for whole protein: P18031
• BLAST for modular domain: 1XBO
• SAS for domain: 1XBO

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: PTPc
• PsiBase: 1XBO
• MINT: whole protein: P18031 or domain: 1XBO
• DOMINO database: P18031
• APID: P18031

• Title: Ptp1B Complexed With Isoxazole Carboxylic Acid
• Experimental Technique: X-ray Diffraction
• Resolution Å: 2.5
• Protein Source: Homo sapiens
• Reference: Zhao et al. 2004 Bioorg Med Chem Let 14, 5543
• Sequence domain: seqA_1xbo2.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 1xbo
• Drugs:
• Phosphorylated residue type:
• Pfam family: PTPc
• Pfam structure: 1XBO
• RCSB_PDB_ID: 1XBO
• SMART: PTPc
• PDBsum (domain): 1XBO
• PDBsum (Ligand): 1XBO
• MSD (summary): 1XBO
• MSD (ligands): 1XBO
• Molecular Surface: 1xbo

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.