INTERNAL ADAN INFORMATION

• Record: 629
• Number: 12
• Inclusion date: 16-III-2005

WHOLE PROTEIN INFORMATION

• Domains within protein: SOS1_HUMAN by SMART
• Basic UniProtKB Entry: SOS1_HUMAN
• InterPro link: SOS1_HUMAN
• Swiss-Prot ENTRY: SOS1_HUMAN
• Swiss-Prot AC number: Q07889
• Sequence: Q07889
• Pfam database: SOS1_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: Q07889
• BLAST for whole protein: Q07889
• SAS for whole protein: Q07889
• BLAST for modular domain: 1XD4
• SAS for domain: 1XD4

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: PH
• PsiBase: 1XD4
• MINT: whole protein: Q07889 or domain: 1XD4
• DOMINO database: Q07889
• APID: Q07889

• Title: Experimentally Phased Structure of Human the Son of Sevenless protein at 4.1 Ang.
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 4.1
• Protein Source: Homo sapiens
• Reference: Sondermann et al. 2004 Cell 119, 393
• Sequence domain: seqA_1xd42.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 1xd4
• Drugs:
• Phosphorylated residue type:
• Pfam family: PH
• Pfam structure: 1XD4
• RCSB_PDB_ID: 1XD4
• SMART: PH
• PDBsum (domain): 1XD4
• PDBsum (Ligand): 1XD4
• MSD (summary): 1XD4
• MSD (ligands): 1XD4
• Molecular Surface: 1xd4

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.