INTERNAL ADAN INFORMATION

• Record: 628
• Number: 11
• Inclusion date: 16-III-2005

WHOLE PROTEIN INFORMATION

• Domains within protein: ARHGC_HUMAN by SMART
• Basic UniProtKB Entry: ARHGC_HUMAN
• InterPro link: ARHGC_HUMAN
• Swiss-Prot ENTRY: ARHGC_HUMAN
• Swiss-Prot AC number: Q9NZN5
• Sequence: Q9NZN5
• Pfam database: ARHGC_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: Q9NZN5
• BLAST for whole protein: Q9NZN5
• SAS for whole protein: Q9NZN5
• BLAST for modular domain: 1X86
• SAS for domain: 1X86

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: PH
• PsiBase: 1X86
• MINT: whole protein: Q9NZN5 or domain: 1X86
• DOMINO database: Q9NZN5
• APID: Q9NZN5

• Title: Crystal Structure Of The Dh/pH Domains Of Leukemia- Assiociated Rhogef In Complex With Rhoa
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 3.22
• Protein Source: Homo sapiens
• Reference: Kristelly et al. 2004 J Biol Chem 279, 47352
• Sequence domain: seqA_1x862.txt
• Peptide sequence of ligand: AAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQA
• Biochemical affinity data for: 1x86
• Drugs:
• Phosphorylated residue type:
• Pfam family: PH
• Pfam structure: 1X86
• RCSB_PDB_ID: 1X86
• SMART: PH
• PDBsum (domain): 1X86
• PDBsum (Ligand): 1X86
• MSD (summary): 1X86
• MSD (ligands): 1X86
• Molecular Surface: 1x86

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.