INTERNAL ADAN INFORMATION

• Record: 582
• Number: 23
• Inclusion date: 23-VIII-2004

WHOLE PROTEIN INFORMATION

• Domains within protein: BRC1_HUMAN by SMART
• Basic UniProtKB Entry: BRC1_HUMAN
• InterPro link: BRC1_HUMAN
• Swiss-Prot ENTRY: BRC1_HUMAN
• Swiss-Prot AC number: P38398
• Sequence: P38398
• Pfam database: BRC1_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: P38398
• BLAST for whole protein: P38398
• SAS for whole protein: P38398
• BLAST for modular domain: 1T15
• SAS for domain: 1T15

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: 1T152_mat 
• iPfam: BRCT
• PsiBase: 1T15
• MINT: whole protein: P38398 or domain: 1T15
• DOMINO database: P38398
• APID: P38398

• Title: CRYSTAL STRUCTURE OF THE BRCA1 BRCT DOMAINS IN COMPLEX WITH THE PHOSPHORYLATED INTERACTING REGION FROM BACH1 HELICASE
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 1.85
• Protein Source: Homo sapiens
• Reference: Clapperton et al. 2004 Nat Struct Mol Biol 11, 512
• Sequence domain: seqA_1t152.txt
• Peptide sequence of ligand: STXPTFNK
• Biochemical affinity data for: 1t15
• Drugs:
• Phosphorylated residue type: Ser
• Pfam family: BRCT
• Pfam structure: 1T15
• RCSB_PDB_ID: 1T15
• SMART: BRCT
• PDBsum (domain): 1T15
• PDBsum (Ligand): 1T15
• MSD (summary): 1T15
• MSD (ligands): 1T15
• Molecular Surface: 1t15

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.