INTERNAL ADAN INFORMATION

• Record: 553
• Number: 18
• Inclusion date: 1-IX-2004

WHOLE PROTEIN INFORMATION

• Domains within protein: CHK2_HUMAN by SMART
• Basic UniProtKB Entry: CHK2_HUMAN
• InterPro link: CHK2_HUMAN
• Swiss-Prot ENTRY: CHK2_HUMAN
• Swiss-Prot AC number: O96017
• Sequence: O96017
• Pfam database: CHK2_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: O96017
• BLAST for whole protein: O96017
• SAS for whole protein: O96017
• BLAST for modular domain: 1GXC
• SAS for domain: 1GXC

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: 1GXC2_mat 
• iPfam: FHA
• PsiBase: 1GXC
• MINT: whole protein: O96017 or domain: 1GXC
• DOMINO database: O96017
• APID: O96017

• Title: FHA DOMAIN FROM HUMAN CHK2 KINASE IN COMPLEX WITH A SYNTHETIC PHOSPHOPEPTIDE
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 2.7
• Protein Source: Homo sapiens
• Reference: Li et al. 2002 Mol Cell 9, 1045
• Sequence domain: seqA_1gxc2.txt
• Peptide sequence of ligand: HFDXYLIR
• Biochemical affinity data for: 1gxc
• Drugs:
• Phosphorylated residue type: Thr
• Pfam family: FHA
• Pfam structure: 1GXC
• RCSB_PDB_ID: 1GXC
• SMART: FHA
• PDBsum (domain): 1GXC
• PDBsum (Ligand): 1GXC
• MSD (summary): 1GXC
• MSD (ligands): 1GXC
• Molecular Surface: 1gxc

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.