INTERNAL ADAN INFORMATION

• Record: 475
• Number: 68
• Inclusion date: 21-VIII-2004

WHOLE PROTEIN INFORMATION

• Domains within protein: PTN6_HUMAN by SMART
• Basic UniProtKB Entry: PTN6_HUMAN
• InterPro link: PTN6_HUMAN
• Swiss-Prot ENTRY: PTN6_HUMAN
• Swiss-Prot AC number: P29350
• Sequence: P29350
• Pfam database: PTN6_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: P29350
• BLAST for whole protein: P29350
• SAS for whole protein: P29350
• BLAST for modular domain: 1GWZ
• SAS for domain: 1GWZ

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: PTPc
• PsiBase: 1GWZ
• MINT: whole protein: P29350 or domain: 1GWZ
• DOMINO database: P29350
• APID: P29350

• Title: CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF THE PROTEIN TYROSINE PHOSPHATASE SHP-1
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 2.5
• Protein Source: Homo sapiens
• Reference: Yang et al. 1998 J Biol Chem 273, 28199
• Sequence domain: seqA_1gwz2.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 1gwz
• Drugs:
• Phosphorylated residue type:
• Pfam family: PTPc
• Pfam structure: 1GWZ
• RCSB_PDB_ID: 1GWZ
• SMART: PTPc
• PDBsum (domain): 1GWZ
• PDBsum (Ligand): 1GWZ
• MSD (summary): 1GWZ
• MSD (ligands): 1GWZ
• Molecular Surface: 1gwz

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.