INTERNAL ADAN INFORMATION

• Record: 451
• Number: 4
• Inclusion date: 1-IX-2004

WHOLE PROTEIN INFORMATION

• Domains within protein: PLK1_HUMAN by SMART
• Basic UniProtKB Entry: PLK1_HUMAN
• InterPro link: PLK1_HUMAN
• Swiss-Prot ENTRY: PLK1_HUMAN
• Swiss-Prot AC number: P53350
• Sequence: P53350
• Pfam database: PLK1_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: P53350
• BLAST for whole protein: P53350
• SAS for whole protein: P53350
• BLAST for modular domain: 1UMW
• SAS for domain: 1UMW

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: Polo box
• PsiBase: 1UMW
• MINT: whole protein: P53350 or domain: 1UMW
• DOMINO database: P53350
• APID: P53350

• Title: STRUCTURE OF A HUMAN PLK1 POLO-BOX DOMAIN/PHOSPHOPEPTIDE COMPLEX
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 1.9
• Protein Source: Homo sapiens
• Reference: Elia et al. 2003 Cell 115, 83
• Sequence domain: seqA_1umw2.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 1umw
• Drugs:
• Phosphorylated residue type: Thr
• Pfam family: Polo box
• Pfam structure: 1UMW
• RCSB_PDB_ID: 1UMW
• SMART: Polo box
• PDBsum (domain): 1UMW
• PDBsum (Ligand): 1UMW
• MSD (summary): 1UMW
• MSD (ligands): 1UMW
• Molecular Surface: 1umw

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.