INTERNAL ADAN INFORMATION

• Record: 449
• Number: 2
• Inclusion date: 1-IX-2004

WHOLE PROTEIN INFORMATION

• Domains within protein: PLK1_HUMAN by SMART
• Basic UniProtKB Entry: PLK1_HUMAN
• InterPro link: PLK1_HUMAN
• Swiss-Prot ENTRY: PLK1_HUMAN
• Swiss-Prot AC number: P53350
• Sequence: P53350
• Pfam database: PLK1_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: P53350
• BLAST for whole protein: P53350
• SAS for whole protein: P53350
• BLAST for modular domain: 1Q4K
• SAS for domain: 1Q4K

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: 1Q4K2_mat 
• iPfam: Polo box
• PsiBase: 1Q4K
• MINT: whole protein: P53350 or domain: 1Q4K
• DOMINO database: P53350
• APID: P53350

• Title: THE POLO-BOX DOMAIN OF PLK1 IN COMPLEX WITH A PHOSPHO-PEPTIDE
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 2.3
• Protein Source: Homo sapiens
• Reference: Cheng et al. 2003 EMBO J 22, 5757
• Sequence domain: seqA_1q4k2.txt
• Peptide sequence of ligand: MQSXPL
• Biochemical affinity data for: 1q4k
• Drugs:
• Phosphorylated residue type: Thr
• Pfam family: Polo box
• Pfam structure: 1Q4K
• RCSB_PDB_ID: 1Q4K
• SMART: Polo box
• PDBsum (domain): 1Q4K
• PDBsum (Ligand): 1Q4K
• MSD (summary): 1Q4K
• MSD (ligands): 1Q4K
• Molecular Surface: 1q4k

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.