INTERNAL ADAN INFORMATION

• Record: 446
• Number: 10
• Inclusion date: 1-IX-2004

WHOLE PROTEIN INFORMATION

• Domains within protein: GGA1_HUMAN by SMART
• Basic UniProtKB Entry: GGA1_HUMAN
• InterPro link: GGA1_HUMAN
• Swiss-Prot ENTRY: GGA1_HUMAN
• Swiss-Prot AC number: Q9UJY5
• Sequence: Q9UJY5
• Pfam database: GGA1_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: Q9UJY5
• BLAST for whole protein: Q9UJY5
• SAS for whole protein: Q9UJY5
• BLAST for modular domain: 1UJJ
• SAS for domain: 1UJJ

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: 1UJJ2_mat 
• iPfam: VHS
• PsiBase: 1UJJ
• MINT: whole protein: Q9UJY5 or domain: 1UJJ
• DOMINO database: Q9UJY5
• APID: Q9UJY5

• Title: VHS DOMAIN OF HUMAN GGA1 COMPLEXED WITH C-TERMINAL PEPTIDE FROM BACE
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 2.6
• Protein Source: Homo sapiens
• Reference: Shiba et al. 2004 Traffic 5, 437
• Sequence domain: seqA_1ujj2.txt
• Peptide sequence of ligand: DDISLLK
• Biochemical affinity data for: 1ujj
• Drugs:
• Phosphorylated residue type: Ser
• Pfam family: VHS
• Pfam structure: 1UJJ
• RCSB_PDB_ID: 1UJJ
• SMART: VHS
• PDBsum (domain): 1UJJ
• PDBsum (Ligand): 1UJJ
• MSD (summary): 1UJJ
• MSD (ligands): 1UJJ
• Molecular Surface: 1ujj

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.