INTERNAL ADAN INFORMATION

• Record: 445
• Number: 9
• Inclusion date: 21-VIII-2004

WHOLE PROTEIN INFORMATION

• Domains within protein: GGA1_HUMAN by SMART
• Basic UniProtKB Entry: GGA1_HUMAN
• InterPro link: GGA1_HUMAN
• Swiss-Prot ENTRY: GGA1_HUMAN
• Swiss-Prot AC number: Q9UJY5
• Sequence: Q9UJY5
• Pfam database: GGA1_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: Q9UJY5
• BLAST for whole protein: Q9UJY5
• SAS for whole protein: Q9UJY5
• BLAST for modular domain: 1PY1
• SAS for domain: 1PY1

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: VHS
• PsiBase: 1PY1
• MINT: whole protein: Q9UJY5 or domain: 1PY1
• DOMINO database: Q9UJY5
• APID: Q9UJY5

• Title: COMPLEX OF GGA1-VHS DOMAIN AND BETA-SECRETASE C-TERMINAL PHOSPHOPEPTIDE
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 2.6
• Protein Source: Homo sapiens
• Reference: He et al. 2003 Biochemistry 42, 12174
• Sequence domain: seqA_1py12.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 1py1
• Drugs:
• Phosphorylated residue type: Ser
• Pfam family: VHS
• Pfam structure: 1PY1
• RCSB_PDB_ID: 1PY1
• SMART: VHS
• PDBsum (domain): 1PY1
• PDBsum (Ligand): 1PY1
• MSD (summary): 1PY1
• MSD (ligands): 1PY1
• Molecular Surface: 1py1

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.