INTERNAL ADAN INFORMATION

• Record: 429
• Number: 24
• Inclusion date: 21-VIII-2004

WHOLE PROTEIN INFORMATION

• Domains within protein: FW1A_HUMAN by SMART
• Basic UniProtKB Entry: FW1A_HUMAN
• InterPro link: FW1A_HUMAN
• Swiss-Prot ENTRY: FW1A_HUMAN
• Swiss-Prot AC number: Q9Y297
• Sequence: Q9Y297
• Pfam database: FW1A_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: Q9Y297
• BLAST for whole protein: Q9Y297
• SAS for whole protein: Q9Y297
• BLAST for modular domain: 1P22
• SAS for domain: 1P22

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: 1P222_mat 
• iPfam: WD40
• PsiBase: 1P22
• MINT: whole protein: Q9Y297 or domain: 1P22
• DOMINO database: Q9Y297
• APID: Q9Y297

• Title: STRUCTURE OF A BETA-TRCP1-SKP1-BETA-CATENIN COMPLEX: DESTRUCTION MOTIF BINDING AND LYSINE SPECIFICITY ON THE SCFBETA-TRCP1 UBIQUITIN LIGASE
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 2.95
• Protein Source: Homo sapiens
• Reference: Wu et al. 2003 Mol Cell 11, 1445
• Sequence domain: seqA_1p222.txt
• Peptide sequence of ligand: YLDXGIHXGAT
• Biochemical affinity data for: 1p22
• Drugs:
• Phosphorylated residue type: Thr
• Pfam family: WD40
• Pfam structure: 1P22
• RCSB_PDB_ID: 1P22
• SMART: WD40
• PDBsum (domain): 1P22
• PDBsum (Ligand): 1P22
• MSD (summary): 1P22
• MSD (ligands): 1P22
• Molecular Surface: 1p22

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.