INTERNAL ADAN INFORMATION

• Record: 424
• Number: 19
• Inclusion date: 21-VIII-2004

WHOLE PROTEIN INFORMATION

• Domains within protein: TLE1_HUMAN by SMART
• Basic UniProtKB Entry: TLE1_HUMAN
• InterPro link: TLE1_HUMAN
• Swiss-Prot ENTRY: TLE1_HUMAN
• Swiss-Prot AC number: Q04724
• Sequence: Q04724
• Pfam database: TLE1_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: Q04724
• BLAST for whole protein: Q04724
• SAS for whole protein: Q04724
• BLAST for modular domain: 1GXR
• SAS for domain: 1GXR

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: WD40
• PsiBase: 1GXR
• MINT: whole protein: Q04724 or domain: 1GXR
• DOMINO database: Q04724
• APID: Q04724

• Title: WD40 REGION OF HUMAN GROUCHO/TLE1
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 1.65
• Protein Source: Homo sapiens
• Reference: Pickles et al. 2002 Structure 10, 751
• Sequence domain: seqA_1gxr2.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 1gxr
• Drugs:
• Phosphorylated residue type: Thr
• Pfam family: WD40
• Pfam structure: 1GXR
• RCSB_PDB_ID: 1GXR
• SMART: WD40
• PDBsum (domain): 1GXR
• PDBsum (Ligand): 1GXR
• MSD (summary): 1GXR
• MSD (ligands): 1GXR
• Molecular Surface: 1gxr

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.