INTERNAL ADAN INFORMATION

• Record: 398
• Number: 66
• Inclusion date: 21-VIII-2004

WHOLE PROTEIN INFORMATION

• Domains within protein: IRS1_HUMAN by SMART
• Basic UniProtKB Entry: IRS1_HUMAN
• InterPro link: IRS1_HUMAN
• Swiss-Prot ENTRY: IRS1_HUMAN
• Swiss-Prot AC number: P35568
• Sequence: P35568
• Pfam database: IRS1_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: P35568
• BLAST for whole protein: P35568
• SAS for whole protein: P35568
• BLAST for modular domain: 1QQG
• SAS for domain: 1QQG

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: PH
• PsiBase: 1QQG
• MINT: whole protein: P35568 or domain: 1QQG
• DOMINO database: P35568
• APID: P35568

• Title: CRYSTAL STRUCTURE OF THE PH-PTB TARGETING REGION OF IRS-1
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 2.3
• Protein Source: Homo sapiens
• Reference: Dhe-Paganon et al. 1999 Proc Natl Acad Sci U S A 96, 8378
• Sequence domain: seqA_1qqg2.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 1qqg
• Drugs:
• Phosphorylated residue type:
• Pfam family: PH
• Pfam structure: 1QQG
• RCSB_PDB_ID: 1QQG
• SMART: PH
• PDBsum (domain): 1QQG
• PDBsum (Ligand): 1QQG
• MSD (summary): 1QQG
• MSD (ligands): 1QQG
• Molecular Surface: 1qqg

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.