INTERNAL ADAN INFORMATION

• Record: 3484
• Number: 37
• Inclusion date: 20-IV-2008

WHOLE PROTEIN INFORMATION

• Domains within protein: SAV1_MOUSE by SMART
• Basic UniProtKB Entry: SAV1_MOUSE
• InterPro link: SAV1_MOUSE
• Swiss-Prot ENTRY: SAV1_MOUSE
• Swiss-Prot AC number: Q8VEB2
• Sequence: Q8VEB2
• Pfam database: SAV1_MOUSE

ALIGNMENT

• BLAST against Swiss-Prot: Q8VEB2
• BLAST for whole protein: Q8VEB2
• SAS for whole protein: Q8VEB2
• BLAST for modular domain: 2DWV
• SAS for domain: 2DWV

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: WW
• PsiBase: 2DWV
• MINT: whole protein: Q8VEB2 or domain: 2DWV
• DOMINO database: Q8VEB2
• APID: Q8VEB2

• Title: Solution Structure Of The Second Ww Domain From Mouse Salvador Homolog 1 Protein (Mww45)
• Experimental Technique: nmr
• Resolution Å: n/a
• Protein Source: Mus musculus
• Reference: Febs Lett. v581 pp. 462-8, 2007
• Sequence domain: SeqA_2DWV2.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 2DWV
• Drugs:
• Phosphorylated residue type: Phosphorylated by STK3 and STK4. Phosphorylation is not required for SAV1 stability and may increase the number of protein binding sites on the scaffold molecule (By similarity)
• Pfam family: WW
• Pfam structure: 2DWV
• RCSB_PDB_ID: 2DWV
• SMART: WW
• PDBsum (domain): 2DWV
• PDBsum (Ligand): 2DWV
• MSD (summary): 2DWV
• MSD (ligands): 2DWV
• Molecular Surface: 2DWV

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.