INTERNAL ADAN INFORMATION

• Record: 3443
• Number: 46
• Inclusion date: 20--IV-2008

WHOLE PROTEIN INFORMATION

• Domains within protein: WDR5_HUMAN by SMART
• Basic UniProtKB Entry: WDR5_HUMAN
• InterPro link: WDR5_HUMAN
• Swiss-Prot ENTRY: WDR5_HUMAN
• Swiss-Prot AC number: P61964
• Sequence: P61964
• Pfam database: WDR5_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: P61964
• BLAST for whole protein: P61964
• SAS for whole protein: P61964
• BLAST for modular domain: 2H9M
• SAS for domain: 2H9M

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: 2H9M2_mat 
• iPfam: WD40
• PsiBase: 2H9M
• MINT: whole protein: P61964 or domain: 2H9M
• DOMINO database: P61964
• APID: P61964

• Title: Wdr5 In Complex With Unmodified H3K4 Peptide
• Experimental Technique: x-ray
• Resolution Å: 1.9
• Protein Source: Homo sapiens
• Reference: Embo J. v25 pp. 4245-52, 2006
• Sequence domain: SeqA_2H9M2.txt
• Peptide sequence of ligand: ARTKQT
• Biochemical affinity data for: 2H9M
• Drugs:
• Phosphorylated residue type:
• Pfam family: WD40
• Pfam structure: 2H9M
• RCSB_PDB_ID: 2H9M
• SMART: WD40
• PDBsum (domain): 2H9M
• PDBsum (Ligand): 2H9M
• MSD (summary): 2H9M
• MSD (ligands): 2H9M
• Molecular Surface: 2H9M

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.