INTERNAL ADAN INFORMATION

• Record: 3427
• Number: 145
• Inclusion date: 20-IV-2008

WHOLE PROTEIN INFORMATION

• Domains within protein: Q63Z43_HUMAN by SMART
• Basic UniProtKB Entry: Q63Z43_HUMAN
• InterPro link: Q63Z43_HUMAN
• Swiss-Prot ENTRY: Q63Z43_HUMAN
• Swiss-Prot AC number: Q63Z43
• Sequence: Q63Z43
• Pfam database: Q63Z43_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: Q63Z43
• BLAST for whole protein: Q63Z43
• SAS for whole protein: Q63Z43
• BLAST for modular domain: 2OOB
• SAS for domain: 2OOB

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: UBQ
• PsiBase: 2OOB
• MINT: whole protein: Q63Z43 or domain: 2OOB
• DOMINO database: Q63Z43
• APID: Q63Z43

• Title: Crystal Structure Of The Uba Domain From Cbl-B Ubiquitin Ligase In Complex With Ubiquitin
• Experimental Technique: x-ray
• Resolution Å: 1.9
• Protein Source: Homo sapiens
• Reference:
• Sequence domain: SeqA_2OOB2.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 2OOB
• Drugs:
• Phosphorylated residue type: Phosphorylated on tyrosine residues upon TCR or BCR activation, and upon various types of cell stimulation; Auto-ubiquitinated upon EGF-mediated cell activation or upon T-cell costimulation by CD28; which promotes proteasomal degradation
• Pfam family: UBQ
• Pfam structure: 2OOB
• RCSB_PDB_ID: 2OOB
• SMART: UBQ
• PDBsum (domain): 2OOB
• PDBsum (Ligand): 2OOB
• MSD (summary): 2OOB
• MSD (ligands): 2OOB
• Molecular Surface: 2OOB

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.