INTERNAL ADAN INFORMATION

• Record: 3349
• Number: 34
• Inclusion date: 20-IV-2008

WHOLE PROTEIN INFORMATION

• Domains within protein: BARD1_HUMAN by SMART
• Basic UniProtKB Entry: BARD1_HUMAN
• InterPro link: BARD1_HUMAN
• Swiss-Prot ENTRY: BARD1_HUMAN
• Swiss-Prot AC number: Q99728
• Sequence: Q99728
• Pfam database: BARD1_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: Q99728
• BLAST for whole protein: Q99728
• SAS for whole protein: Q99728
• BLAST for modular domain: 2NTE
• SAS for domain: 2NTE

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: BRCT
• PsiBase: 2NTE
• MINT: whole protein: Q99728 or domain: 2NTE
• DOMINO database: Q99728
• APID: Q99728

• Title: Crystal Structure Of The Bard1 Brct Domains
• Experimental Technique: x-ray
• Resolution Å: 1.9
• Protein Source: Homo sapiens
• Reference: Biochemistry v46 pp. 7706-12, 2007
• Sequence domain: SeqA_2NTE2.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 2NTE
• Drugs:
• Phosphorylated residue type: Processed during apoptosis. The homodimer is more susceptible to proteolytic cleavage than the BARD1/BRCA1 heterodimer
• Pfam family: BRCT
• Pfam structure: 2NTE
• RCSB_PDB_ID: 2NTE
• SMART: BRCT
• PDBsum (domain): 2NTE
• PDBsum (Ligand): 2NTE
• MSD (summary): 2NTE
• MSD (ligands): 2NTE
• Molecular Surface: 2NTE

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.