INTERNAL ADAN INFORMATION

• Record: 3312
• Number: 193
• Inclusion date: 20-IV-2008

WHOLE PROTEIN INFORMATION

• Domains within protein: HTRA2_HUMAN by SMART
• Basic UniProtKB Entry: HTRA2_HUMAN
• InterPro link: HTRA2_HUMAN
• Swiss-Prot ENTRY: HTRA2_HUMAN
• Swiss-Prot AC number: O43464
• Sequence: O43464
• Pfam database: HTRA2_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: O43464
• BLAST for whole protein: O43464
• SAS for whole protein: O43464
• BLAST for modular domain: 2PZD
• SAS for domain: 2PZD

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: 2PZD2_mat 
• iPfam: PDZ
• PsiBase: 2PZD
• MINT: whole protein: O43464 or domain: 2PZD
• DOMINO database: O43464
• APID: O43464

• Title: Crystal Structure Of The Htra2/Omi Pdz Domain Bound To A Phage-Derived Ligand (Wtmfwv)
• Experimental Technique: x-ray
• Resolution Å: 2.75
• Protein Source: Homo sapiens
• Reference: Protein Sci. v16 pp. 1738-50, 2007
• Sequence domain: SeqA_2PZD2.txt
• Peptide sequence of ligand: GWTMFWV
• Biochemical affinity data for: 2PZD
• Drugs:
• Phosphorylated residue type: Autoproteolytically activated
• Pfam family: PDZ
• Pfam structure: 2PZD
• RCSB_PDB_ID: 2PZD
• SMART: PDZ
• PDBsum (domain): 2PZD
• PDBsum (Ligand): 2PZD
• MSD (summary): 2PZD
• MSD (ligands): 2PZD
• Molecular Surface: 2PZD

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.