INTERNAL ADAN INFORMATION

• Record: 3308
• Number: 189
• Inclusion date: 20-IV-2008

WHOLE PROTEIN INFORMATION

• Domains within protein: HTRA3_HUMAN by SMART
• Basic UniProtKB Entry: HTRA3_HUMAN
• InterPro link: HTRA3_HUMAN
• Swiss-Prot ENTRY: HTRA3_HUMAN
• Swiss-Prot AC number: P83110
• Sequence: P83110
• Pfam database: HTRA3_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: P83110
• BLAST for whole protein: P83110
• SAS for whole protein: P83110
• BLAST for modular domain: 2P3W
• SAS for domain: 2P3W

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: PDZ
• PsiBase: 2P3W
• MINT: whole protein: P83110 or domain: 2P3W
• DOMINO database: P83110
• APID: P83110

• Title: Crystal Structure Of The Htra3 Pdz Domain Bound To A Phage- Derived Ligand (Fgrwv)
• Experimental Technique: x-ray
• Resolution Å: 1.7
• Protein Source: Homo sapiens
• Reference: Protein Sci. v16 pp. 2454-71, 2007
• Sequence domain: SeqA_2P3W2.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 2P3W
• Drugs:
• Phosphorylated residue type:
• Pfam family: PDZ
• Pfam structure: 2P3W
• RCSB_PDB_ID: 2P3W
• SMART: PDZ
• PDBsum (domain): 2P3W
• PDBsum (Ligand): 2P3W
• MSD (summary): 2P3W
• MSD (ligands): 2P3W
• Molecular Surface: 2P3W

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.