INTERNAL ADAN INFORMATION

• Record: 3304
• Number: 185
• Inclusion date: 20-IV-2008

WHOLE PROTEIN INFORMATION

• Domains within protein: DLG1_HUMAN by SMART
• Basic UniProtKB Entry: DLG1_HUMAN
• InterPro link: DLG1_HUMAN
• Swiss-Prot ENTRY: DLG1_HUMAN
• Swiss-Prot AC number: Q12959
• Sequence: Q12959
• Pfam database: DLG1_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: Q12959
• BLAST for whole protein: Q12959
• SAS for whole protein: Q12959
• BLAST for modular domain: 2OQS
• SAS for domain: 2OQS

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: 2OQS2_mat 
• iPfam: PDZ
• PsiBase: 2OQS
• MINT: whole protein: Q12959 or domain: 2OQS
• DOMINO database: Q12959
• APID: Q12959

• Title: Structure Of The Hdlg/Sap97 Pdz2 In Complex With Hpv-18 Papillomavirus E6 Peptide
• Experimental Technique: nmr
• Resolution Å: n/a
• Protein Source: Homo sapiens
• Reference: Biochemistry v46 pp. 10864-74, 2007
• Sequence domain: SeqA_2OQS2.txt
• Peptide sequence of ligand: RRETQV
• Biochemical affinity data for: 2OQS
• Drugs:
• Phosphorylated residue type: Phosphorylation of Ser-232 regulates association with GRIN2A. Isoform 2 is phosphorylated on Ser-698. Isoform 3 is phosphorylated on Ser-665 (By similarity)
• Pfam family: PDZ
• Pfam structure: 2OQS
• RCSB_PDB_ID: 2OQS
• SMART: PDZ
• PDBsum (domain): 2OQS
• PDBsum (Ligand): 2OQS
• MSD (summary): 2OQS
• MSD (ligands): 2OQS
• Molecular Surface: 2OQS

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.