INTERNAL ADAN INFORMATION

• Record: 3279
• Number: 160
• Inclusion date: 20-IV-2008

WHOLE PROTEIN INFORMATION

• Domains within protein: AFAD_HUMAN by SMART
• Basic UniProtKB Entry: AFAD_HUMAN
• InterPro link: AFAD_HUMAN
• Swiss-Prot ENTRY: AFAD_HUMAN
• Swiss-Prot AC number: P55196
• Sequence: P55196
• Pfam database: AFAD_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: P55196
• BLAST for whole protein: P55196
• SAS for whole protein: P55196
• BLAST for modular domain: 2EXG
• SAS for domain: 2EXG

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: PDZ
• PsiBase: 2EXG
• MINT: whole protein: P55196 or domain: 2EXG
• DOMINO database: P55196
• APID: P55196

• Title: Making Protein-Protein Interactions Drugable: Discovery Of Low-Molecular-Weight Ligands For The Af6 Pdz Domain
• Experimental Technique: nmr
• Resolution Å: n/a
• Protein Source: Homo sapiens
• Reference: Angew.Chem.Int.Ed.Engl. v45 pp. 3790-5, 2006
• Sequence domain: SeqA_2EXG2.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 2EXG
• Drugs:
• Phosphorylated residue type:
• Pfam family: PDZ
• Pfam structure: 2EXG
• RCSB_PDB_ID: 2EXG
• SMART: PDZ
• PDBsum (domain): 2EXG
• PDBsum (Ligand): 2EXG
• MSD (summary): 2EXG
• MSD (ligands): 2EXG
• Molecular Surface: 2EXG

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.