INTERNAL ADAN INFORMATION

• Record: 3241
• Number: 359
• Inclusion date: 20-IV-2008

WHOLE PROTEIN INFORMATION

• Domains within protein: HCK_HUMAN by SMART
• Basic UniProtKB Entry: HCK_HUMAN
• InterPro link: HCK_HUMAN
• Swiss-Prot ENTRY: HCK_HUMAN
• Swiss-Prot AC number: P08631
• Sequence: P08631
• Pfam database: HCK_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: P08631
• BLAST for whole protein: P08631
• SAS for whole protein: P08631
• BLAST for modular domain: 2OJ2
• SAS for domain: 2OJ2

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: 2OJ22_mat 
• iPfam: SH3
• PsiBase: 2OJ2
• MINT: whole protein: P08631 or domain: 2OJ2
• DOMINO database: P08631
• APID: P08631

• Title: Nmr Structure Analysis Of The Hematopoetic Cell Kinase Sh3 Domain Complexed With An Artificial High Affinity Ligand (Pd1)
• Experimental Technique: nmr
• Resolution Å: n/a
• Protein Source: Homo sapiens
• Reference: J.Mol.Biol. v365 pp. 1517-32, 2007
• Sequence domain: SeqA_2OJ22.txt
• Peptide sequence of ligand: HSKYPLPPLPSL
• Biochemical affinity data for: 2OJ2
• Drugs:
• Phosphorylated residue type: Isoform p59-HCK contains a N-myristoyl glycine at position 3 (By similarity). Isoform p59-HCK contains a S-palmitoyl cysteine at position 3 (By similarity)
• Pfam family: SH3
• Pfam structure: 2OJ2
• RCSB_PDB_ID: 2OJ2
• SMART: SH3
• PDBsum (domain): 2OJ2
• PDBsum (Ligand): 2OJ2
• MSD (summary): 2OJ2
• MSD (ligands): 2OJ2
• Molecular Surface: 2OJ2

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.