INTERNAL ADAN INFORMATION

• Record: 3237
• Number: 355
• Inclusion date: 20-IV-2008

WHOLE PROTEIN INFORMATION

• Domains within protein: Q14020_HUMAN by SMART
• Basic UniProtKB Entry: Q14020_HUMAN
• InterPro link: Q14020_HUMAN
• Swiss-Prot ENTRY: Q14020_HUMAN
• Swiss-Prot AC number: Q14020
• Sequence: Q14020
• Pfam database: Q14020_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: Q14020
• BLAST for whole protein: Q14020
• SAS for whole protein: Q14020
• BLAST for modular domain: 2O88
• SAS for domain: 2O88

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: 2O882_mat 
• iPfam: SH3
• PsiBase: 2O88
• MINT: whole protein: Q14020 or domain: 2O88
• DOMINO database: Q14020
• APID: Q14020

• Title: Crystal Structure Of The N114A Mutant Of Abl-Sh3 Domain Complexed With A Designed High-Affinity Peptide Ligand: Implications For Sh3-Ligand Interactions
• Experimental Technique: x-ray diffraction
• Resolution Å: 1.75
• Protein Source: Homo sapiens
• Reference:
• Sequence domain: SeqA_2O882.txt
• Peptide sequence of ligand: APSYSPPPPP
• Biochemical affinity data for: 2O88
• Drugs:
• Phosphorylated residue type:
• Pfam family: SH3
• Pfam structure: 2O88
• RCSB_PDB_ID: 2O88
• SMART: SH3
• PDBsum (domain): 2O88
• PDBsum (Ligand): 2O88
• MSD (summary): 2O88
• MSD (ligands): 2O88
• Molecular Surface: 2O88

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.