INTERNAL ADAN INFORMATION

• Record: 3225
• Number: 343
• Inclusion date: 20-IV-2008

WHOLE PROTEIN INFORMATION

• Domains within protein: CD2AP_HUMAN by SMART
• Basic UniProtKB Entry: CD2AP_HUMAN
• InterPro link: CD2AP_HUMAN
• Swiss-Prot ENTRY: CD2AP_HUMAN
• Swiss-Prot AC number: Q9Y5K6
• Sequence: Q9Y5K6
• Pfam database: CD2AP_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: Q9Y5K6
• BLAST for whole protein: Q9Y5K6
• SAS for whole protein: Q9Y5K6
• BLAST for modular domain: 2J7I
• SAS for domain: 2J7I

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: 2J7I2_mat 
• iPfam: SH3
• PsiBase: 2J7I
• MINT: whole protein: Q9Y5K6 or domain: 2J7I
• DOMINO database: Q9Y5K6
• APID: Q9Y5K6

• Title: Atypical Polyproline Recognition By The Cms N-Terminal Sh3 Domain. Cms:Cd2 Heterodimer
• Experimental Technique: x-ray diffraction
• Resolution Å: 2.9
• Protein Source: Homo sapiens
• Reference: J.Biol.Chem. v281 pp. 38845-53, 2006
• Sequence domain: SeqA_2J7I2.txt
• Peptide sequence of ligand: GPPLPRPRV
• Biochemical affinity data for: 2J7I
• Drugs:
• Phosphorylated residue type: Phosphorylated on tyrosine residues; probably by c-Abl, Fyn and c-Src
• Pfam family: SH3
• Pfam structure: 2J7I
• RCSB_PDB_ID: 2J7I
• SMART: SH3
• PDBsum (domain): 2J7I
• PDBsum (Ligand): 2J7I
• MSD (summary): 2J7I
• MSD (ligands): 2J7I
• Molecular Surface: 2J7I

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.