INTERNAL ADAN INFORMATION

• Record: 3164
• Number: 282
• Inclusion date: 20-IV-2008

WHOLE PROTEIN INFORMATION

• Domains within protein: SH3K1_HUMAN by SMART
• Basic UniProtKB Entry: SH3K1_HUMAN
• InterPro link: SH3K1_HUMAN
• Swiss-Prot ENTRY: SH3K1_HUMAN
• Swiss-Prot AC number: Q96B97
• Sequence: Q96B97
• Pfam database: SH3K1_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: Q96B97
• BLAST for whole protein: Q96B97
• SAS for whole protein: Q96B97
• BLAST for modular domain: 2BZ8
• SAS for domain: 2BZ8

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: 2BZ83_mat 
• iPfam: SH3
• PsiBase: 2BZ8
• MINT: whole protein: Q96B97 or domain: 2BZ8
• DOMINO database: Q96B97
• APID: Q96B97

• Title: N-Terminal Sh3 Domain Of Cin85 Bound To Cbl-B Peptide
• Experimental Technique: x-ray diffraction
• Resolution Å: 2.0
• Protein Source: Homo sapiens
• Reference: Nat.Struct.Mol.Biol. v12 pp. 972-9, 2005
• Sequence domain: SeqA_2BZ83.txt
• Peptide sequence of ligand: PARPPKPRPRR
• Biochemical affinity data for: 2BZ8
• Drugs:
• Phosphorylated residue type: Monoubiquitinated by CBL and CBLB after EGF stimulation; probably on its C-terminus
• Pfam family: SH3
• Pfam structure: 2BZ8
• RCSB_PDB_ID: 2BZ8
• SMART: SH3
• PDBsum (domain): 2BZ8
• PDBsum (Ligand): 2BZ8
• MSD (summary): 2BZ8
• MSD (ligands): 2BZ8
• Molecular Surface: 2BZ8

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.