INTERNAL ADAN INFORMATION

• Record: 3146
• Number: 219
• Inclusion date: 20-IV-2008

WHOLE PROTEIN INFORMATION

• Domains within protein: SOCS6_HUMAN by SMART
• Basic UniProtKB Entry: SOCS6_HUMAN
• InterPro link: SOCS6_HUMAN
• Swiss-Prot ENTRY: SOCS6_HUMAN
• Swiss-Prot AC number: O14544
• Sequence: O14544
• Pfam database: SOCS6_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: O14544
• BLAST for whole protein: O14544
• SAS for whole protein: O14544
• BLAST for modular domain: 2VIF
• SAS for domain: 2VIF

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: 2VIF2_mat 
• iPfam: SH2
• PsiBase: 2VIF
• MINT: whole protein: O14544 or domain: 2VIF
• DOMINO database: O14544
• APID: O14544

• Title: Crystal Structure Of Socs6 Sh2 Domain In Complex With A C- Kit Phosphopeptide
• Experimental Technique: x-ray diffraction
• Resolution Å: 1.45
• Protein Source: Homo sapiens
• Reference:
• Sequence domain: SeqA_2VIF2.txt
• Peptide sequence of ligand: NNyVYIDPT
• Biochemical affinity data for: 2VIF
• Drugs:
• Phosphorylated residue type:
• Pfam family: SH2
• Pfam structure: 2VIF
• RCSB_PDB_ID: 2VIF
• SMART: SH2
• PDBsum (domain): 2VIF
• PDBsum (Ligand): 2VIF
• MSD (summary): 2VIF
• MSD (ligands): 2VIF
• Molecular Surface: 2VIF

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.