INTERNAL ADAN INFORMATION

• Record: 3145
• Number: 218
• Inclusion date: 20-IV-2008

WHOLE PROTEIN INFORMATION

• Domains within protein: PK3CA_HUMAN by SMART
• Basic UniProtKB Entry: PK3CA_HUMAN
• InterPro link: PK3CA_HUMAN
• Swiss-Prot ENTRY: PK3CA_HUMAN
• Swiss-Prot AC number: P42336
• Sequence: P42336
• Pfam database: PK3CA_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: P42336
• BLAST for whole protein: P42336
• SAS for whole protein: P42336
• BLAST for modular domain: 2RD0
• SAS for domain: 2RD0

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: SH2
• PsiBase: 2RD0
• MINT: whole protein: P42336 or domain: 2RD0
• DOMINO database: P42336
• APID: P42336

• Title: Structure Of A Human P110Alpha/P85Alpha Complex
• Experimental Technique: x-ray diffraction
• Resolution Å: 3.05
• Protein Source: Homo sapiens
• Reference: Science v318 pp. 1744-8, 2007
• Sequence domain: SeqA_2RD02.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 2RD0
• Drugs:
• Phosphorylated residue type:
• Pfam family: SH2
• Pfam structure: 2RD0
• RCSB_PDB_ID: 2RD0
• SMART: SH2
• PDBsum (domain): 2RD0
• PDBsum (Ligand): 2RD0
• MSD (summary): 2RD0
• MSD (ligands): 2RD0
• Molecular Surface: 2RD0

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.