INTERNAL ADAN INFORMATION

• Record: 3144
• Number: 217
• Inclusion date: 20-IV-2008

WHOLE PROTEIN INFORMATION

• Domains within protein: ZAP70_HUMAN by SMART
• Basic UniProtKB Entry: ZAP70_HUMAN
• InterPro link: ZAP70_HUMAN
• Swiss-Prot ENTRY: ZAP70_HUMAN
• Swiss-Prot AC number: P43403
• Sequence: P43403
• Pfam database: ZAP70_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: P43403
• BLAST for whole protein: P43403
• SAS for whole protein: P43403
• BLAST for modular domain: 2OZO
• SAS for domain: 2OZO

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: SH2
• PsiBase: 2OZO
• MINT: whole protein: P43403 or domain: 2OZO
• DOMINO database: P43403
• APID: P43403

• Title: Autoinhibited Intact Human Zap-70
• Experimental Technique: x-ray diffraction
• Resolution Å: 2.6
• Protein Source: Homo sapiens
• Reference: Cell(Cambridge,Mass.) v129 pp. 735-46, 2007
• Sequence domain: SeqA_2OZO3.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 2OZO
• Drugs:
• Phosphorylated residue type: Phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation. Tyr-319 phosphorylation is essential for full activity
• Pfam family: SH2
• Pfam structure: 2OZO
• RCSB_PDB_ID: 2OZO
• SMART: SH2
• PDBsum (domain): 2OZO
• PDBsum (Ligand): 2OZO
• MSD (summary): 2OZO
• MSD (ligands): 2OZO
• Molecular Surface: 2OZO

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.