INTERNAL ADAN INFORMATION

• Record: 3136
• Number: 209
• Inclusion date: 20-IV-2008

WHOLE PROTEIN INFORMATION

• Domains within protein: Q9WVM5_MOUSE by SMART
• Basic UniProtKB Entry: Q9WVM5_MOUSE
• InterPro link: Q9WVM5_MOUSE
• Swiss-Prot ENTRY: Q9WVM5_MOUSE
• Swiss-Prot AC number: Q9WVM5
• Sequence: Q9WVM5
• Pfam database: Q9WVM5_MOUSE

ALIGNMENT

• BLAST against Swiss-Prot: Q9WVM5
• BLAST for whole protein: Q9WVM5
• SAS for whole protein: Q9WVM5
• BLAST for modular domain: 2HDX
• SAS for domain: 2HDX

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: 2HDX2_mat 
• iPfam: SH2
• PsiBase: 2HDX
• MINT: whole protein: Q9WVM5 or domain: 2HDX
• DOMINO database: Q9WVM5
• APID: Q9WVM5

• Title: Crystal Structure Of The Src Homology-2 Domain Of Sh2-B In Complex With Jak2 Ptyr813 Phosphopeptide
• Experimental Technique: x-ray diffraction
• Resolution Å: 2.35
• Protein Source: Mus musculus
• Reference:
• Sequence domain: SeqA_2HDX2.txt
• Peptide sequence of ligand: TPDyELLTE
• Biochemical affinity data for: 2HDX
• Drugs:
• Phosphorylated residue type: Phosphorylated on tyrosine residues in response to IGF-I and PDGF stimulation
• Pfam family: SH2
• Pfam structure: 2HDX
• RCSB_PDB_ID: 2HDX
• SMART: SH2
• PDBsum (domain): 2HDX
• PDBsum (Ligand): 2HDX
• MSD (summary): 2HDX
• MSD (ligands): 2HDX
• Molecular Surface: 2HDX

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.