INTERNAL ADAN INFORMATION

• Record: 3135
• Number: 208
• Inclusion date: 20-IV-2008

WHOLE PROTEIN INFORMATION

• Domains within protein: Q9WVM5_MOUSE by SMART
• Basic UniProtKB Entry: Q9WVM5_MOUSE
• InterPro link: Q9WVM5_MOUSE
• Swiss-Prot ENTRY: Q9WVM5_MOUSE
• Swiss-Prot AC number: Q9WVM5
• Sequence: Q9WVM5
• Pfam database: Q9WVM5_MOUSE

ALIGNMENT

• BLAST against Swiss-Prot: Q9WVM5
• BLAST for whole protein: Q9WVM5
• SAS for whole protein: Q9WVM5
• BLAST for modular domain: 2HDV
• SAS for domain: 2HDV

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: SH2
• PsiBase: 2HDV
• MINT: whole protein: Q9WVM5 or domain: 2HDV
• DOMINO database: Q9WVM5
• APID: Q9WVM5

• Title: Crystal Structure Of The Src Homology-2 Domain Of The Adapter Protein Sh2-B
• Experimental Technique: x-ray diffraction
• Resolution Å: 2.0
• Protein Source: Mus musculus
• Reference: J.Mol.Biol. v361 pp. 69-79, 2006
• Sequence domain: SeqA_2HDV2.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 2HDV
• Drugs:
• Phosphorylated residue type: Phosphorylated on tyrosine residues in response to IGF-I and PDGF stimulation
• Pfam family: SH2
• Pfam structure: 2HDV
• RCSB_PDB_ID: 2HDV
• SMART: SH2
• PDBsum (domain): 2HDV
• PDBsum (Ligand): 2HDV
• MSD (summary): 2HDV
• MSD (ligands): 2HDV
• Molecular Surface: 2HDV

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.