INTERNAL ADAN INFORMATION

• Record: 319
• Number: 74
• Inclusion date: 21-VIII-2004

WHOLE PROTEIN INFORMATION

• Domains within protein: HRA2_HUMAN by SMART
• Basic UniProtKB Entry: HRA2_HUMAN
• InterPro link: HRA2_HUMAN
• Swiss-Prot ENTRY: HRA2_HUMAN
• Swiss-Prot AC number: O43464
• Sequence: O43464
• Pfam database: HRA2_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: O43464
• BLAST for whole protein: O43464
• SAS for whole protein: O43464
• BLAST for modular domain: 1LCY
• SAS for domain: 1LCY

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: PDZ
• PsiBase: 1LCY
• MINT: whole protein: O43464 or domain: 1LCY
• DOMINO database: O43464
• APID: O43464

• Title: CRYSTAL STRUCTURE OF THE MITOCHONDRIAL SERINE PROTEASE HTRA2
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 2
• Protein Source: Homo sapiens
• Reference: Li et al. 2002 Nat Struct Biol 9, 436
• Sequence domain: seqA_1lcy2.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 1lcy
• Drugs:
• Phosphorylated residue type:
• Pfam family: PDZ
• Pfam structure: 1LCY
• RCSB_PDB_ID: 1LCY
• SMART: PDZ
• PDBsum (domain): 1LCY
• PDBsum (Ligand): 1LCY
• MSD (summary): 1LCY
• MSD (ligands): 1LCY
• Molecular Surface: 1lcy

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.