INTERNAL ADAN INFORMATION

• Record: 32
• Number: 41
• Inclusion date: 21-VIII-2004

WHOLE PROTEIN INFORMATION

• Domains within protein: GRB2_MOUSE by SMART
• Basic UniProtKB Entry: GRB2_MOUSE
• InterPro link: GRB2_MOUSE
• Swiss-Prot ENTRY: GRB2_MOUSE
• Swiss-Prot AC number: Q60631
• Sequence: Q60631
• Pfam database: GRB2_MOUSE

ALIGNMENT

• BLAST against Swiss-Prot: Q60631
• BLAST for whole protein: Q60631
• SAS for whole protein: Q60631
• BLAST for modular domain: 1GBR
• SAS for domain: 1GBR

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: 1GBR2_mat 
• iPfam: SH3
• PsiBase: 1GBR
• MINT: whole protein: Q60631 or domain: 1GBR
• DOMINO database: Q60631
• APID: Q60631

• Title: ORIENTATION OF PEPTIDE FRAGMENTS FROM SOS PROTEINS BOUND TO THE N-TERMINAL SH3 DOMAIN OF GRB2 DETERMINED BY NMR SPECTROSCOPY
• Experimental Technique: NMR
• Resolution Å: n/a
• Protein Source: Mus musculus
• Reference: Wittekind et al. 1994 Biochemistry 33, 13531
• Sequence domain: seqA_1gbr2.txt
• Peptide sequence of ligand: SPLLPKLPPKTYKRE
• Biochemical affinity data for: 1gbr
• Drugs:
• Phosphorylated residue type: n/a
• Pfam family: SH3
• Pfam structure: 1GBR
• RCSB_PDB_ID: 1GBR
• SMART: SH3
• PDBsum (domain): 1GBR
• PDBsum (Ligand): 1GBR
• MSD (summary): 1GBR
• MSD (ligands): 1GBR
• Molecular Surface: 1gbr

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.