INTERNAL ADAN INFORMATION

• Record: 308
• Number: 63
• Inclusion date: 21-VIII-2004

WHOLE PROTEIN INFORMATION

• Domains within protein: NHR1_HUMAN by SMART
• Basic UniProtKB Entry: NHR1_HUMAN
• InterPro link: NHR1_HUMAN
• Swiss-Prot ENTRY: NHR1_HUMAN
• Swiss-Prot AC number: O14754
• Sequence: O14754
• Pfam database: NHR1_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: O14754
• BLAST for whole protein: O14754
• SAS for whole protein: O14754
• BLAST for modular domain: 1GQ4
• SAS for domain: 1GQ4

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: PDZ
• PsiBase: 1GQ4
• MINT: whole protein: O14754 or domain: 1GQ4
• DOMINO database: O14754
• APID: O14754

• Title: STRUCTURAL DETERMINANTS OF THE NHERF INTERACTION WITH BETA2AR AND PDGFR
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 1.9
• Protein Source: Homo sapiens
• Reference: Karthikeyan et al. 2002 J Biol Chem 277, 18973
• Sequence domain: seqA_1gq42.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 1gq4
• Drugs:
• Phosphorylated residue type:
• Pfam family: PDZ
• Pfam structure: 1GQ4
• RCSB_PDB_ID: 1GQ4
• SMART: PDZ
• PDBsum (domain): 1GQ4
• PDBsum (Ligand): 1GQ4
• MSD (summary): 1GQ4
• MSD (ligands): 1GQ4
• Molecular Surface: 1gq4

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.