INTERNAL ADAN INFORMATION

• Record: 269
• Number: 154
• Inclusion date: 21-VIII-2004

WHOLE PROTEIN INFORMATION

• Domains within protein: PTNB_HUMAN by SMART
• Basic UniProtKB Entry: PTNB_HUMAN
• InterPro link: PTNB_HUMAN
• Swiss-Prot ENTRY: PTNB_HUMAN
• Swiss-Prot AC number: Q06124
• Sequence: Q06124
• Pfam database: PTNB_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: Q06124
• BLAST for whole protein: Q06124
• SAS for whole protein: Q06124
• BLAST for modular domain: 2SHP
• SAS for domain: 2SHP

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: SH2
• PsiBase: 2SHP
• MINT: whole protein: Q06124 or domain: 2SHP
• DOMINO database: Q06124
• APID: Q06124

• Title: TYROSINE PHOSPHATASE SHP-2
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 2
• Protein Source: Homo sapiens
• Reference: Hof et al. 1998 Cell 92, 441
• Sequence domain: seqA_2shp2.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 2shp
• Drugs:
• Phosphorylated residue type: Tyr
• Pfam family: SH2
• Pfam structure: 2SHP
• RCSB_PDB_ID: 2SHP
• SMART: SH2
• PDBsum (domain): 2SHP
• PDBsum (Ligand): 2SHP
• MSD (summary): 2SHP
• MSD (ligands): 2SHP
• Molecular Surface: 2shp

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.