INTERNAL ADAN INFORMATION

• Record: 2562
• Number: 10
• Inclusion date: 16-IV-2007

WHOLE PROTEIN INFORMATION

• Domains within protein: SMAD3_HUMAN by SMART
• Basic UniProtKB Entry: SMAD3_HUMAN
• InterPro link: SMAD3_HUMAN
• Swiss-Prot ENTRY: SMAD3_HUMAN
• Swiss-Prot AC number: P84022
• Sequence: P84022
• Pfam database: SMAD3_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: P84022
• BLAST for whole protein: P84022
• SAS for whole protein: P84022
• BLAST for modular domain: 1U7F
• SAS for domain: 1U7F

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: MH2
• PsiBase: 1U7F
• MINT: whole protein: P84022 or domain: 1U7F
• DOMINO database: P84022
• APID: P84022

• Title: Crystal Structure of the phosphorylated Smad3/Smad4 heterotrimeric complex
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 2.6
• Protein Source: Homo sapiens
• Reference: Mol.Cell v15 pp. 813-23, 2004
• Sequence domain: SeqA_1U7F2.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 1U7F
• Drugs:
• Phosphorylated residue type:
• Pfam family: MH2
• Pfam structure: 1U7F
• RCSB_PDB_ID: 1U7F
• SMART: MH2
• PDBsum (domain): 1U7F
• PDBsum (Ligand): 1U7F
• MSD (summary): 1U7F
• MSD (ligands): 1U7F
• Molecular Surface: 1U7F

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.